Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 108 for “"Biology, Physiology"”.
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Some like it cold: interactions between the northern frog biting mosquito, Culex territans (Walker 1856), and its amphibian hosts
… about this mosquito. This work dives into the biology, physiology, and vector potential of this mosquito species to provide critical insights into understanding the evolution of feeding on endotherms as well as the importance of Cx. territans to amphibian health. The first study investigates …
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Foraging Ecology & Conservation Physiology of the Mottled Petrel, Pterodroma inexpectata, with Applications for Maximising the Success of Petrel Conservation
… basic species knowledge, including reproductive biology, physiology and spatial extent. Efforts to obtain information to aid the research and conservation of seabirds often requires manipulation, including handling of both adults and chicks. Repeated exposure to stressors, including environmental …
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Energetic costs of toxicant metabolism in rainbow trout ( Oncorhynchus mykiss)
Aquatic ecosystems are continuously exposed to a variety of environmental toxicants including polychlorinated biphenyls (PCBs). A portion of the energy assimilated by the fish is dedicated to detoxification. This study investigates the changes in energetic demands associated with increased …
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Tissue Salvage in the Non-reperfused Myocardium Mediated by (the absence of the circadian rhythm gene) mPer2 and (the receptor tyrosine kinase) EphrinA1
Alterations in circadian rhythm have been associated with numerous cardiovascular pathologies. In project 1, we tested the hypothesis that functional mutation of the Per2 circadian clock gene would provide cardioprotection to mice that had undergone permanent coronary ligation to induce myocardial …
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Role of Aryl Hydrocarbon Receptor in Circadian Rhythm: A Novel Pathway to Dioxin Toxicity
… perspectives in both dioxin toxicology and chronobiology.
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Mechanism of Spermatogonial Stem Cell Regulation by ETV2
… of germ cells. Hence understanding of SSC biology is essential to comprehend the complex process of spermatogenesis and has implications in stem cell therapeutics, male infertility and the development of a male contraceptive. Various factors essential for SSC regulation have been …
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Progesterone Receptor Regulation of the Gene Networks That Control Ovulation in Mice
In a pubertal human female, the mid-cycle surge of luteinizing hormone (LH) induces ovulation, releasing a fertilizable egg from a mature ovarian follicle. Although ovulation is a physiologically well-characterized event, the underlying molecular processes remain poorly understood. Based on …
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DNA Repair, Redox Regulation and Modulation of Estrogen Receptor Alpha Mediated Transcription
Interaction of estrogen receptor alpha (ERalpha) with 17beta-estradiol (E2) facilitates binding of the receptor to estrogen response elements (EREs) in target genes, which in turn leads to recruitment of coregulatory proteins. To better understand how estrogen-responsive genes are regulated, our …
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Nutritional Regulation of Cholesterol 7alpha Hydroxylase (Cyp7a1) Expression
The combined studies on understanding the molecular basis for the nutritional regulation of CYP7A1 expression may provide new insights into the changes in cholesterol, lipid, and bile acid metabolism in diabetes and obesity.
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Identification and Classification of Novel Gene Products Involved in Development and Regeneration in Xenopus Laevis
A cornea-lens transdifferentiation-specific cDNA library has been used to characterize new molecular events in lens regeneration. Most of these genes are also expressed during lens development, illustrating the similarity between mechanisms of development and regeneration. A subset of genes; whose …
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Effects of Exercise on Immune Function in Young, Adult, and Aged Mice: Increased Survival and a Decrease in Inflammation
We have previously shown that moderate exercise for 4 days during a mounting immune response significantly increases survival during influenza virus (A/PR/8/34) infection in mice. We hypothesized that this brief duration of exercise resulted in a decreased level of lung histopathology while …
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Neuroplastic Adaptations to Exercise Training and Detraining
Neuronal activity has been shown to be attenuated in cardiorespiratory and locomotor centers (CRLC) of the brain in response to a single bout of exercise in trained (TR) versus untrained (UN) animals, but the mechanisms remain obscure. Dendritic branching patterns of seven brain areas associated …
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Physical Activity, Disablement, and Quality of Life in Long-Term Care Residents: A Feasibility Study
In an effort to address the need for more research on older adults in residential care facilities this study proposes to examine the feasibility of recruiting, encouraging compliance, and obtaining reliable data among this population. Secondly, to address the ambiguity surrounding disablement and …
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Physiological, Behavioral and Reproductive Responses of Black -Capped Vireos and White -Eyed Vireos to Human Disturbance
I conducted research on effects of human activity on a federally-listed endangered bird species, the Black-capped Vireo (Vireo atricapilla ) and a closely related congeneric, the White-eyed Vireo ( Vireo griseus) on Fort Hood Military Reservation, Texas. My research determines effects of human …
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The Role of Estrogen Receptor Alpha in Epididymal Sperm Structure and Function
Male mice deficient in ERalpha (ERalphaKO mice) are infertile and sperm recovered from the cauda epididymis exhibit reduced motility and fail to fertilize eggs in vitro. These effects on sperm appear to result from defective epididymal function and not a direct effect on spermatogenesis, as …
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Intrinsic Spectroscopic Tumor Markers Revealed by Double-Differential Analysis of Near-Infrared Absorption Spectra
… have shown to be sensitive to changes in breast physiology from disease by quantifying total hemoglobin (oxyhemoglobin and deoxyhemoglobin), oxygen saturation, fat content, and water content. Tumors display changes in these parameters; however, it is debatable whether they are specific …
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Biochemical Characterization of CXCR4 Interactions With HIV -1, Natural Ligands and De Novo Designed Inhibitors
… applications of chemokines as probes of receptor biology and inhibitors of pathological processes, a major problem with the lack of receptor selectivity of natural chemokines must be overcome. Here, we combined total protein synthesis with modular modifications to generate a new class of unnatural …
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Roles of Zinc in Skeletal Muscle Cells Growth
Zinc deficiency impairs skeletal muscle growth in both humans and animals independently of decreased food intake. Insulin-like growth factor (IGF) is the primary regulator of postnatal muscle growth and there is substantial evidence that the effects of zinc deficiency alter IGF mediated muscle …
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Impact of Dietary Carbohydrate and Protein Levels on Carbohydrate Metabolism
The third objective evaluated differential tissue responses in gene expression and metabolic signaling in liver, muscle, and adipose tissue associated with diets containing 58%, 40%, or 25% of energy as CARB. These diets represent high (HC), moderate (MC), and low (LC) CARB amounts within the …
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Expression and Function of Basigin During Implantation in the Mouse
Taken together, our data suggested that basigin plays multiple roles during implantation by regulating uterine stromal cell differentiation, stimulating MMP production and inducing the expression of pro-inflammatory genes.
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