Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 898 for “"Biology, Molecular."”.
-
An icon of conservation biology: molecular ecology of greater prairie chicken (Tympanuchus cupido pinnatus) in Illinois
Made available in DSpace on 2012-02-01T00:54:10Z (GMT). No. of bitstreams: 3 Mussmann_Steven.pdf: 683774 bytes, checksum: 783a5d90b1d907163a8ff0be4f4ae602 (MD5) license.txt: 4065 bytes, checksum: 70e81c1b4097a058a975809a4d7b50aa (MD5) Mussmann_Steven.docx: 961193 bytes, checksum: …
-
Modeling Molecular Structures with Intrinsic Diffusion Models
… one hundred years ago, the field of structural biology has strived to understand and analyze the properties of molecules and their interactions by studying the structure that they take in 3D space. However, a fundamental challenge with this approach has been the dynamic nature of these …
-
Modulation of Transcription Factor Chromatin Association and Gene Transcription Program in Embryonic Stem Cell and Triple Negative Breast Cancer by Poly (ADP-Ribose) Polymerase 1
… in this field. Using a combination of cell biology, molecular biology, genomics and biochemistry methods, I investigated the functions of PARP-1 in regulating gene transcription program in mouse embryonic stem cells and human triple negative breast cancer cells. I found that in mouse …
-
Structural and Functional Studies of the Unconventional Proteobacterial Transcription Activator Crl in Complex with the Transcription Machinery
… interactions with core RNAP. Using structural biology, molecular biology, biochemical and biophysical techniques, I gained novel insight into the unusual mechanism of Crl. This research validated and expanded on previous studies delineating the Crl/σ<sup>S</sup> interaction and showed how a …
-
The Development of Assays for Detecting Proximal Phosphorylation and Covalent Modification of Proteins
… disciplines including medicinal chemistry, molecular recognition and chemical biology. Achieving success in bioassays represents important milestones in many pharmaceutical pipelines and disease diagnostics, and as such, must be designed and fine-tuned to produce meaningful, robust, and …
-
Statistics for Learning Genetics
… study investigated the knowledge and skills that biology students may need to help them understand statistics/mathematics as it applies to genetics. The data are based on analyses of current representative genetics texts, practicing genetics professors' perspectives, and more directly, students' …
-
Trafficking motifs in potassium channels
… density of these channels. Techniques in cell biology, molecular biology and biochemistry were employed to identify the molecular basis of Sar1-GTPase dependent ER exit of the KATP and hERG channels in COPII vesicles. Blocking the cargo binding sites on the Sec24 protein of the COPII coat with …
-
Mechanistic studies of Fusobacterium genetic and defense systems
… which has led to hindrance in the study of their biology, molecular mechanisms, and pathogenesis. The genetic intractability of Fusobacterium is an obstacle for the development of future treatments for diseases associated with these anaerobic bacteria. Therefore, the creation of tools to enhance …
-
Electrical And Magnetic Separation Of Particles
… well as in biomedical application, such as cell biology, molecular genetics, biotechnological production, clinical diagnostics, and therapeutics. A lot of particle separation technologies using various mechanics in terms of the differences in the physical or physico-chemical properties of the …
-
Solid-Binding Peptides Enable Biomolecular Surface Assemblies and Mineralization
… for solids with the purpose of using them as molecular building blocks in materials synthesis, assembly, and formation. As part of developing these tools for biotechnology, solid-binding peptides found via several methods were used in a variety of proof-of-principle applications. The research …
-
Single Molecule Resolution Study of Circadian Chromatin Dynamics Regulated by the Pioneer Transcription Factor CLOCK:BMAL1
… TF that promotes rhythmic chromatin opening, the molecular mechanism of how it cooperates with other TFs to regulate circadian transcription remains poorly understood. To address this, we adapted single-molecule footprinting (SMF), a technique that simultaneously captures nucleosome occupancy and …
-
Molecular cloning of three genes encoding SNF1/AMPK protein kinases from Drosophila melanogaster.
… in a number of different organisms and recent molecular and biochemical evidence has revealed that the mammalian AMP-activated protein kinases (AMPKs), known to regulate fatty acid and sterol metabolism in response to stress, represent the mammalian homologues of SNF1. Three novel Drosophila …
-
Molecular characterization of the cell division gene ftsZ in Neisseria gonorrhoeae.
… In efforts to understand cell division at the molecular level in N. gonorrhoeae, the ftsZ gene has been identified and preliminary characterization is reported. The gonococcal ftsZ consists of a 1179 bp open reading frame, encoding a 41.3 kDa protein. Sequence analysis has shown the gonococcal …
-
Cloning and characterization of novel kinases from embryonic cells.
Protein tyrosine kinases (PYKs) play key regulatory roles in the control of cell growth and differentiation. Attempts to identify novel PYKs through expression cloning strategies have led to the identification of a novel family of protein kinases, referred to as dual specificity kinases (DSKs). In …
-
Distinct Functions of POT1 in Telomere Protection and Length Regulation
<p>Telomeres are DNA-protein structures that protect eukaryotic chromosome ends from illegitimate recombination and degradation. Telomeres become shortened with each cell division unless telomerase, a reverse transcriptase, is activated. In addition to playing a protective role of chromosome ends, …
-
Development Of Trophoblast Lined Blood Spaces In The Mouse Placenta
Trophoblast giant cells (TGCs) have a unique ability to form pseudo-vascular spaces in the placenta. Proper development of these maternal blood spaces is crucial for successful pregnancy outcomes. Unlike blood vessels in other organs, the vascular space in placenta is line by non-endothelial TGCs. …
-
Transcriptional regulation of the inducible orphan nuclear receptornur77.
Transcriptional regulation of the inducible orphan nuclear receptornur77.
-
Regulation of transcription initiation at guanine + cytosine-rich promoters.
Regulation of transcription initiation at guanine + cytosine-rich promoters.
-
Domains of the NR2A and NR2B subunits involved in NMDA receptor current modulation by PKC.
Domains of the NR2A and NR2B subunits involved in NMDA receptor current modulation by PKC.
-
ORGANIZATION AND FUNCTION OF SIMIAN VIRUS 40 ORIGIN REGION SEQUENCES IN LATE GENE TRANSCRIPTION AND REPLICATION.
ORGANIZATION AND FUNCTION OF SIMIAN VIRUS 40 ORIGIN REGION SEQUENCES IN LATE GENE TRANSCRIPTION AND REPLICATION.
Page 1 of 45