Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 344 for “"Biologically active"”.
-
Biologically active molecules from marine microalgae
Diatoms are unicellular photosynthetic microalgae responsible for approximately 40% of marine primary productivity. This algal class has traditionally been regarded as providing the bulk of the food that sustains the marine food chain to top consumers and important fisheries. However, this …
-
Synthesis of biologically active heterocyclic compounds
… library of 5-deazaflavins were synthesised and biologically tested producing some interesting biological results.
-
Biologically Active Compounds From Caribbean Sponges
… The corresponding esters were relatively inactive as antibacterial agents but because they were more stable and easier to purify, they were the compounds chosen for the structural studies. Structure elucidation of the purified esters was based on interpretation of the compounds high …
-
Size adjustable separation of biologically active molecules
Separation of biologically active molecules (BAM's) is a problem for the pharmaceutical and biotechnology industries. Current technologies addressing this problem require too many techniques, toxic additives, and time to filter desired materials. As a result, a new technology is needed. The …
-
Biologically active compounds from tunicates and a sponge
Part I. Studies on structures and biological activities of didemnins. Six new cyclic depsipeptides related to didemnins were isolated from a relatively polar extract of the tunicate T. solidum. Their structures were determined by spectroscopic techniques and chemical degradations as follows: …
-
CHEMOENZYMATIC APPROACHES TO THE PREPARATION OF BIOLOGICALLY ACTIVE COMPOUNDS
Biologically active compounds are usually polyfunctional molecules bearing one or more stereocenters. Enzyme catalyzed transformations are well suitable for their preparation since they act in a very mild and selective manner. The study of three selected biocatalyzed transformations has been the …
-
Development of New Synthetic Approaches to Biologically-Active Peptides
… disulfide crosslinking with hexafluorobenzene in biologically active p53 peptides. Residues of the biologically active pDI peptide that had been shown to be tolerant to substitution were replaced with cysteine (analogues), including D-cysteine, homocysteine and penicillamine. It was found that …
-
Synthesis of Biologically Active Cytoprotective and Anticancer Small Molecules
Cancer is the most common cause of disease-related fatalities in the United States of America. It is estimated that more then half a million people per year will die from various forms of cancer. One of the defining characteristics of cancer is an uncontrollable growth of cells. Regardless of its …
-
Biologically active compounds from a clam and a tunicate
Part I. Isolation and characterization of sphingosine analogs from the clam Spisula polynyma. Extracts of the Stimpson surf clam, Spisula polynyma, were found to cause a distinct alteration of the morphology of L1210 murine leukemia cells in which the compounds develop sharp points, usually located …
-
Guided growth : design and computation of biologically active materials
… renewable, self-assembling, self-healing, and biologically active. Our rapidly growing ability to re-program living cells to produce materials they would not produce in their natural state presents future possibilities as far-reaching as growing houses from seeds. This dissertation explores …
-
Studies on some biologically active natural products from Tulbaghia Alliacea
It is believed that early humans had knowledge of how to use traditional medicinal plants, but the knowledge has been partially lost as society underwent various changes leading to new civilizations. The aim of this study was to isolate and identify natural product constituents from Tulbaghia …
-
Design and synthesis of novel biologically active flavones and isoflavones
… scaffold to synthesize analogues of a bioactive natural product was also explored. The synthesized analogues were tested against cancer cells with results showing that a number of these compounds displayed promising anti-cancer effects. The construction of 4-arylisoflavan scaffold started …
-
The isolation, structure, and membrane interactions of biologically active peptides.
… venoms of arachnids are an abundant source of biologically active peptides with a great potential for use in therapeutic pharmacology. Over millions of years of evolution, the chemical arsenals of a multitude of species have produced a vast collection of peptides that have potent and selective …
-
Design of an automated purification system for biologically-active macromolecules
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2001.
-
The synthesis of biologically active oxa-polyamine analogues, homologues and conjugates.
Polyamines such as putrescine, spermidine, and spermine and their derivatives are found to be present in every living cell. Being products of amino acid metabolism polyamines play an important role in normal cell function and replication. Analogues, homologues, and derivatives of natural polyamines …
-
Synthetic Studies Of Biologically Active Molecules: Irl 2500, Bruceantin, And Biliatresone
Part 1: Carbon monoxide (CO) is a poisonous gas that binds to hemoglobin, preventing oxygen transport to the tissues. CO poisoning causes ~50,000 emergency room visits per year. Treatments for CO poisoning are extremely limited. IRL 2500 is a small molecule allosteric effector of hemoglobin that …
-
Microwave-Mediated Hetero Diels-Alder reaction: Synthesis of biologically active compounds
… nature and play a key role in a huge number of biologically important molecules including some of the most significant for human beings. A powerful tool for the synthesis of such compounds is the hetero Diels-Alder reaction (HDA), that involve a [4+2] cycloaddition reaction between heterodienes …
Page 1 of 18