Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 142 for “"Biological system"”.
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Gene expression-based screening of inhibitors of signal transduction
… applicable markers to monitor activity of the biological system. Gene expression-based screening is based on the assumption that introduction of a compound into biological system would affect directly or indirectly the gene expression, initiating an elaborate expression response to the …
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From Biology to Algorithms
This thesis describes a path from a model of a biological system to a biologically-inspired algorithm. The thesis commences with a discussion of the principled design of biologically-inspired algorithms. It is argued that modelling a biological system can be tremendously helpful in eventual …
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Phenomenological models in biological physics : cell growth and pluripotency maintenance
… challenge in quantitatively modeling a biological system is that the system often involves many components and just as dizzying number of interactions among those components. To further complicate matters, the parameters that characterize those interactions and components, like the rates …
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Design, analysis, and fabrication of a prototype non-invasive system for assessment of biological and synthetic tissues
A new instrument system for the non-invasive assessment of biological systems has been designed, built and validated. This system utilizes the optical characteristics of a biological system to assess both its static and dynamic response over time. The changes in the optical properties can then be …
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Design of an Embedded Fluorescence Imaging System for Implantable Optical Neural Recording
… brain is the most complex and least understood biological system known to man. New imaging techniques are providing scientists with an entirely new perspec- tive on the study of the functional brain at a neural circuit level, enabling in-depth understanding of both physiological processes and …
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Activity-Based Protein Profiling Reveals Changes to the Regulation of Enzymatic Activity by the Hepatitis C Virus
Biological systems, their physical structure and their functions, are built, maintained, and controlled by the activity of enzymes. Understanding how enzymes contribute to the regulation of various pathways and processes allows us to gain a deeper understanding of the entirety of the biological …
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Environmental remediation and biofuel production through nanoparticle stimulation of yeast
Artificially photosynthetic systems aim to store solar energy and chemically reduce carbon dioxide. These systems have been developed in order to use light to drive processes for carbon fixation into biomass and/or liquid fuels. We have developed a hybrid-biological system that manages both …
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Dynamics of Self -Organization of Ramified Patterns in an Electromechanical System
… of how tree structures self-organize in the system. We are also interested, more generally, in how the detailed structure of ramified patterns affects the properties of systems that use them for transportation. Therefore, in collaboration with researchers at the Santa Fe Institute, we …
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Meso : a virtual musculature for humanoid motor control
Humanoid behavior requires a system with access to humanoid variables. Our humanoid robot, Cog, has two arms that are structurally similar to those of humans; however, the sensory system only provides a sense of strain and position. This thesis describes a model of the human energy metabolism that …
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Inference for auto-regulatory genetic networks using diffusion process approximations
… Differential Equations (SDEs) which approximate biological systems. In principle EA can be applied to any scalar-valued SDE as long as a transformation (known as Lamperti transform) exists that sets the (new) infinitesimal variance to unity. We explore the numerical limitations of this …
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The development and applications of Fourier transformed relaxation measurements in nuclear magnetic resonance (NMR)
… decays which are very common in chemical and biological system. Based on this method, many interesting studies can now be done with NMR. The details of this method are presented with a comparison between our method and the conventional method and results and discussion of some applications.
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A biological simulator using a stochastic approach for synthetic biology
… In this thesis, I designed and implemented a biological system simulator that will enable synthetic biologists to simulate their systems before they put time into building actual physical cells. Improvements to the current simulators in use include a design that enables extensions in …
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INTRACELLULAR PATTERN FORMATION OF F-BAR PROTEIN FBP17
Living cells exhibit various dynamic biological patterns in the forms of waves and oscillations. Increasing attention is paid to their functions in efficient and robust signal transduction. However, whether plasma membrane plays an active role in wave propagation remains to be answered. In this …
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Study of mutation, mutants, and repair in the blue-green alga Agmenellum quadruplicatum
… of cells? The blue-green algae provide a new biological system in which mutagenic agents and the theories of mutagenesis may be checked and correlated with other biological systems. The second area concerns the study of the mutants themselves. It is anticipated that mutants may be useful in …
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Ontology-Driven and Network–Enabled Systems Biology Case Studies
… genetic or environmental manipulation of a biological system affects the expression of thousands of genes and proteins. This study requires a shift from the conventional pure hypothesis-driven approach to an integrated approach--systems biology method. Systems biology studies the …
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Synthesis of insightful algorithms
… ""Insightful Algorithm"" as an analog of a biological system which is capable of fusing environmental observations with multiple predictive models of its process and/or its relationship to its environment, in the form of a Generalized Body of Evidence, which it then uses to respond to …
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Applications of SLIM (Spectral Localization by Imaging) localization technique
… inhomogeneity in the composition of living systems, applications of nuclear magnetic resonance spectroscopy (MRS) to the biological system require techniques that can discriminate signals according to their spatial origins and detect signals only from the operator-designated regions. These …
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Engineering micro-perfusable scaffolds for MesoPhysiological Systems using projection Micro-StereoLithography
MicroPhysiological Systems (MPS) are in vitro models that capture the complexity of human organs at miniature scale by recreating the native microenvironment of resident cells. These systems offer promising alternatives to in vivo animal models for the development of new drugs, disease modeling and …
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The Effect of Nutritional Conditions on Floc Formation in Zoogloea ramigera.
… importance in the activated sludge process of biological system, treatment waste treatment. In such a generally begins with the settling of large suspended solids from the influent wastewater. The liquid is then channeled into the reaction basin where soluble organic compounds undergo …
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