Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Biological products."”.
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Enhancing mineral nutrient availability and corn productivity with biostimulants
… a new technology has been discussed, namely, biological products. These products have a wide variety of uses but are typically intended to increase crop growth, relieve crop stresses, enhance the availability of soil mineral nutrients, improve the accumulation of mineral nutrients, and …
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Regulatory issues concerning the preclinical testing of synthetic peptides
<p>Any new drug or biological product undergoes rigorous testing in animals and humans for review by the United States Food and Drug Administration (FDA) before it becomes available for human use. A sponsor files an investigational new drug (IND) application with the FDA with supporting animal …
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Mangrolide A, A Novel Marine Derived Polyketide with Selective Antibiotic Activity
The ability of nature to produce complex, biologically active compounds has inspired researchers throughout history. The isolation of these molecules has been instrumental in the discovery of many medicinal compounds, especially to combat infections caused by pathogenic bacteria. Antibiotic …
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Synthetic Studies of the Rubellin Natural Products
… our studies on the rubellin class of natural products, and our investigation of a rearrangement reaction of reactive iodonium ylide intermediates. First described are select syntheses of complex anthraquinone monomers and dimers within the past 20 years. The scientific community has found deep …
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Investigation of the Discoipyrroles and Other Marine Bacteria Derived Natural Products
Natural products are a rich source of scientific innovation. These chemical compounds are canonically celebrated as biomedical tools or synthetic chemistry feats. Discovery of new chemical compounds has benefited from the study of natural product biosynthesis, or the methods by which they are …
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Precursor-Directed Identification of Natural Product Scaffolds
… of medicinal potency and exploration of novel biological activity. Previous work with Streptomyces variabilis has demonstrated that natural products that incorporate non-enzymatic transformation can be exploited for the rapid generation of analogs. Herein we demonstrate a general methodology to …
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Using Multiple Screening Strategies to Biologically and Chemically Characterize Natural Products
Natural products play an important role in the discovery and development of therapeutics and biological probes. However, in recent decades therapeutic screening efforts have moved away from using natural product libraries, instead opting for large synthetic molecule library. This move has …
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Increased Risk of Cutaneous Immune-Related Adverse Events in Patients Treated with Talimogene Laherparepvec and Immune Checkpoint Inhibitors: A Multi-Hospital Cohort Study
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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A Study of Female and Minority Representation in Clinical Trials and Patterns of Loading Dose Use in Biologic Therapies for Hidradenitis Suppurativa and Psoriasis
This thesis includes 2 separate documents: [Part One] A Study of Female and Minority Representation in Clinical Trials and [Part Two] Patterns of Loading Dose Use in Biologic Therapies for Hidradenitis Suppurativa and Psoriasis.
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Indigenous knowledge on utilization aspects and nutritional profiling of selected edible wild fruits from Zambia.
… sweetness, and sour taste. Processing of products such as jams, juices and fermented beverages was reported in isolated cases. The wild fruits under investigation were reported to have medicinal uses that include stopping diarrhoea, boosting the immune system, increasing blood levels and …
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Reassortment of bluetongue virus vaccine serotypes in cattle
… BTV serotypes from Bottle B of the Onderstepoort Biological Products (OBP) vaccine (BTV serotype 3, 8, 9, 10 and 11), while the second group was infected with the same vaccine serotypes and simultaneously infected with a wild type BTV serotype 4. Blood samples were collected daily from the animals …
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Development of a novel bioreactor and systems for suspension cell culture in biopharmaceutical production
… cellular machinery for the production of complex biological products. These cells provide proper post-translational processing machinery for recombinant protein expression to acquire the desired folding for optimal activity. With this advantage, mammalian cells have become the preferred choice for …