Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 82 for “"Biological information"”.
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Extracting biological information from DNA-biomolecule interactions using machine learning and statistics
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-12-01
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Statistical physics and biological information : hydrophobicity patterns in protein design and differential motif finding in DNA
… identification of DNA motifs--short patterns in biological sequences--is essential. Common examples of motifs include transcription factor binding sites in promoter regions of co-regulated genes and exonic and intronic splicing enhancers ...
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Epigenetic modelling: DNA methylation and working towards model parameterisation
… The data curation includes biomedical and biological information. An efficient method was devised to extract biological information from the literature to process, manage and upgrade data. We present a Deterministic Finite Automata (DFA) model for the DNA methylation mechanism controlled by …
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Beyond The Dvh - Spatial And Biological Radiotherapy Treatment Planning
<p><strong>Purpose</strong>: Both spatial and biological information are necessary in order to perform true optimization of a treatment plan and for predicting clinical outcome. The goal of this work is to develop an enhanced treatment plan evaluation tool which incorporates biological parameters …
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Protein-DNA Binding: Discovering Motifs and Distinguishing Direct from Indirect Interactions
… tools: it can incorporate different types of biological information (e.g., nucleosome positioning information) to guide the search for DNA binding sites toward regions where these sites are more likely to occur (e.g., nucleosome-free regions). </p><p>We use transcription factor (TF) binding …
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Life history study of red stumpnose (Chrysoblephus gibbiceps), a South African endemic seabream
… the most iconic species within this family, yet biological information is lacking on this species. Six hundred and seventy-eight specimens were collected from 1986 to 2012, ranging in size from 165 to 600 mm fork length. All specimens were dissected and morphological measurements taken. Gonads, …
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Marine biological valuation as a decision support tool for marine management
… describes the development and application of a biological instrument that can be used for marine management, and more specifically for marine spatial planning. A biological valuation methodology was developed that compiles all available biological information of a certain area in one indicator …
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Bioassessment and the Partitioning of Community Composition and Diversity Across Spatial Scales in Wetlands of the Bonneville Basin
… facing appropriate management is the lack of biological information for determining which wetlands should receive protection priorities based on the presence of viable, functioning characteristics. The purpose of this dissertation project was to obtain biological information needed to support …
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BioDig : architecture for integrating heterogeneous biological data repositories using ontologies
… experiments generate vast quantities of biological information that are stored in autonomous data repositories distributed across the World Wide Web. There exists a need to integrate information from multiple data repositories for the purposes of data mining; however, current methods of …
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Single Cell Study of Malaria and Antimalarial Drug Impacts on Platelets and Mast Cells
… responders against foreign substances within a biological system. Understanding how the fundamental mechanisms of these two cell types act in a diseased vs. healthy environment is particularly important for any therapeutic approach. By using an electrochemical single cell technique, carbon-fiber …
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DNA Microarray Data Analysis and Mining: Affymetrix Software Package and In-House Complementary Packages
… that a standardized analysis tool, incorporating biological information about the genes is needed in order to better interpret the microarray study. To address the data management problem, in-house programs, including scripts and a database, were designed. The in-house programs were also used to …
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Large Margin Random Forests On Mixed Type Data
Incorporating various sources of biological information is important for biological discovery. For example, genes have a multi-view representation. They can be represented by features such as sequence length and physical-chemical properties. They can also be represented by pairwise similarities, …
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Encoding the Body: Critically Assessing the Collection and Uses of Biometric Information
… States. Biometric technologies scan the body's biological information for the purposes of identification. They include digital fingerprinting, iris scanning and facial-recognition technology. I investigate the ways that policies governing the collection of biometric information understand …
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Structure, Function, and Interaction in Protein Language Models
… of protein language models in decoding complex biological information, thereby contributing to advancements in computational biology.
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No hea te kiore : MtDNA variation in Rattus exulans : a model for human colonisation and contact in prehistoric Polynesia
… reconstruction, originally developed for biological systematics, is a tool which is increasingly being used for anthropological studies addressing the problems of population origins and settlement patterns. Given the nature of the phylogenetic model, it is expected that phylogenetic …
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Biological Network-based Approaches to The Functional Analysis of miRNAs in Prostate Cancer
… in a complex and efficient manner to achieve biological functions and cellular phenotypes. Traditional biology studied these components one at a time, yielding limited insights about the way a cell functions. It is now apparent that the most effective way to understand how the cell works is to …
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Computational algorithm development for epigenomic analysis
… The potential utility of finding meaningful biological information was demonstrated by the applications on real datasets. For biological question driven data mining, several important topics were selected for algorithm developments, including hypothesis-driven insulator prediction, unbiased …
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Concurrency Optimization for Integrative Network Analysis
… which examines gene expression data with prior biological information to reliably identify significant genes and proteins. Using random resampling with replacement (bootstrapping or bagging) is essential to confident results but is computationally demanding as multiple iterations of the network …
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Statistical and computational approaches for the analysis of high-throughput epigenomic data /
… where the TOP-seq signal can be used to obtain biological information.
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