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Showing 1 to 20 of 21 for “"Biological assay"”.
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Method of biological assay of Gastrin and its application to the study of human tissue
The relatively small number of cases in this series, aggravated by the need for further division into subgroups, makes interpretation difficult. The situation is made worse by a number of factors as yet unknown, e.g., the effect of anaesthesia and duration of operation on the gastrin content, the …
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Effect of Processing Temperatures on the Utilization of Lysine in Meat Meal Proteins as Measured by Microbiological, Chemical and Biological Assay Methods
Made available in DSpace on 2014-12-09T14:28:56Z (GMT). No. of bitstreams: 1 6607793.pdf: 3723386 bytes, checksum: d6abed055a3b9f8e60646bf90e3d8ca8 (MD5) Previous issue date: 1966
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Electrochemical Detection of Anti-Biofilm Activity Using Unnatural Amino Acid-Containing Antimicrobial Peptides
… for this purpose. Traditional methods such as biological assays are the standard by which antibiotics are judged, but they have their drawbacks, such as the lengthy test times and the costs associated with it and the reagents. Electrochemical biosensors can remedy some of those drawbacks by …
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The Selection of Aptamers to CD20 and Their Application as Inhibitors of Complement Dependent Cytotoxicity
… effect with anti-CD20 antibody; and in a biological assay possessed a protective capacity, limiting the extent of antibody induced complement dependent cytotoxicity. Overall, genetic transfection is a novel targeted approach of ligand generation, producing aptamers endowed with both …
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The influence of the ration of the cow on vitamin C content of milk
… of milk. The determinations were made by the biological assay method and by the chemical titration method. The cows were given four kinds of rations. Similar determinations have been made by other workers. A brief resume of their technique and conclusions follows: From the results of this …
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Studies on the chemistry of taxol
… the activity of all the derivatives in a tubulin assay was determined. A study of the deacylation and reacylation reactions of baccatin 111 was carried out in order to find conditions suitable for the preparation of 2-debenzoylbaccatin Ill , and thus 2-debenzoyltaxol. Finally, the reactions of …
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A PERTURB-SEQ SATURATION MUTAGENESIS APPROACH TO DISSECT THE MOLECULAR BASES OF GENETIC DISEASES
… protein variants in a single high throughput biological assay. As proof of principle, we decided to apply it to mutagenize two regions of P63 (a portion of the DNA Binding Domain and the SAM domain), a transcription factor that, besides an oncogenic function, is mainly a regulator of skin …
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Arthropod and vertebrate determinants for horizontal transmission of Rickettsia felis
… in naturally infected fleas, we developed a biological assay to infect naïve fleas. This is the first demonstration of oral acquisition and persistent R. felis-infection of fleas fed an R. felis-infected bloodmeal. Lastly, we describe the initial results of a murine model of R. felis …
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Bioactive Peptides as Antibacterial Agents and Visual Transduction
… treat severe MRSA infections. The chemistry and biological assay results of synthesized peptides submitted for evaluation will be discussed in greater detail. Secondly, peripherin 2 (PRPH2) is a photoreceptor specific glycoprotein essential for proper formation of the rod and cone photoreceptor …
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Biosolubilization of K-silicates in pelitic rock by Acidithiobacillus thiooxidans
… Verdete rock (VR), was evaluated by means of a biological assay using A. thiooxidans. Erlenmeyer flasks containing 9 K medium, bacterial culture and VR were incubated at 30 °C at times ranging from 0 to 49 d. After the incubation times, the filtrate and solid phase were collected. The solid …
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Elastomeric Stamping: Design Considerations for Long -Term Maintenance of Neuronal Networks
… and static water contact angles. As a biological assay, B104 neuroblastoma cells were plated on microstamped glass coverslips. Results indicated that the stamping and photoresist patterning procedures are equivalent, having an average pattern compliance of 52.6 +/- 4.4% compared to 54.6 …
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Cell-Fiber Interactions: A New Route to Mechano-Biological Investigations in Developmental and Disease Biology
… work using suspended fibers as a new in vitro biological assay has revealed that cells are able to sense and respond to changes in fiber curvature and structural stiffness as evidenced by alterations to cytoskeleton arrangement, including focal adhesion cluster lengths and nucleus shape …
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Tick toxinology : isolation and characterisation of the toxin from the Australian paralysis tick, Ixodes holocyclus
… mainly due to the insensitivity of the biological assay, the minute quantities present and the reported labile nature of the neurotoxin. This dissertation describes the identification, final purification, partial characterisation and preliminary structural characteristics of the …
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Mechanistic and Synthetic Studies of Oxidopyrylium Cycloaddition Reactions
… primarily explored acid-mediated approaches to biologically active highly oxygenated tropolones. However, the reductive ring opening provided a facile route to a novel A-C colchicine analog. Additionally, the A-C analog synthesized was shown to be highly atropisomerically stable, with computed …
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Memory, metals and neurotrophins
… and those where the neurotrophins exert their biological activity. Metal ions can directly modulate their activities, through conformational changes, and/or indirectly by activating their downstream signaling in a neurotrophin-independent mode. Despite the importance of these modulations, there …
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Antischistosomal structure-activity relationships of nitrated n-phenyl benzamide derivatives.
… adult worms and also using a different in vitro biological assay method could not be deduced. There is need, therefore, to consider resynthesizing the front-runner compound by further research, test it on both juvenile and adult worms using the same in vitro assay method as the newly synthesized …
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Antischistosomal structure-activity relationships of nitrated n-phenyl benzamide derivatives.
… adult worms and also using a different in vitro biological assay method could not be deduced. There is need, therefore, to consider resynthesizing the front-runner compound by further research, test it on both juvenile and adult worms using the same in vitro assay method as the newly synthesized …
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The Medicalization of Stress: Hans Selye and the Transformation of the Postwar Medical Marketplace
… endocrinologist Hans Selye's concept of biological stress, guiding him to develop a highly individualistic and commercially-appealing disease model that complimented major interests of the postwar medical marketplace: the state, the corporation and the consumer. In the mid-1930s Selye …
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Multiplexed Photometry And Fluorimetry Using Multiple Frequency Channels
… window. It enables us to perform multi-parameter biological analysis at lower costs and less complexity. Multiple monochromatic light sources, each with a unique wavelength, are electronically modulated at distinct frequencies, and their combined light emission is directed to the sample detection …
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