Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 241 for “"Biological Activities"”.
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Biological activities of Lavandula angustifolia essential oil
Zuzana Bílková, Biologické účinky silice Levandule úzkolisté, diplomová práce, Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové, vedoucí diplomové práce: PharmDr. Jan Martin, PhD., Hradec Králové, 2013, 72 stran. Diplomová práce s názvem "Biologické účinky silice Levandule …
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Studies on biological activities of Scottish plants.
This thesis describes the investigation of 48 species from 26 different plant families for their bioactive properties as antioxidants, antibacterial and general toxicity. There are 45 species indigenous or naturalised to Scotland. Three Centaurea species from Turkey were also investigated to …
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Design, Syntheses and Biological Activities of Paclitaxel Analogs
… 3.55 were evaluated for their antiproliferative activities against the A2780 cell lines. Analogs 3.50-3.52 and 3.55 which were designed to adopt the T-taxol conformation showed similar antiproliferative activities compared to their open-chain counterparts. They were all much less active than …
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Biological activities and antidiabetic potential of novel peptides from frog secretions
… to Tigerinin-HR4), they exhibited distinct biological activities. <br/><br/>In Chapter 3, the detailed function and correlative mechanisms of novel phylloseptin peptide Phylloseptin-PBu were described. We showed that Phylloseptin-PBu could induce a dose-dependent insulinotropic activity in …
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Isolation, Structures, Synthesis and Biological Activities of Non-Mammalian Vertebrate Endothelins
… to exhibit a wide variety of pharmacological activities and may play diverse pathophysiological roles in cardiovascular diseases. ET was first isolated from the supernatant of cultured porcine aortic endothelial cells and analysis of a human genomic library identified three structurally …
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Chemo-morphological characterisation and some biological activities of pelargonium sidoides DC.
… that P. sidoides extracts possess anti-microbial activities against some of the tested microorganisms which are significant pathogens in humans. P. sidoides roots have the potential for the treatment of diarrhea.
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Phytochemical studies on natural products and their biological activities against Trypanosoma
… human communities. One plant considered to have biological effects is Holy Basil (Ocimum sanctum L.), with pre-clinical screening uncovering many compounds with effects against bacteria, anaphylaxis, histamines, and diabetes as well as with wound healing and radio-protective effects, including …
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Discovering the Biological Activities of Maltose Derivatives for Controlling Bacterial Multicellular Behaviors
… E. coli was found to be critical for antibiofilm activities of brominated furanones against E. coli. The lasI protein on P. aeruginosa is a known homologue of the E. coli SdiA protein. It was found that the brominated furanones were antagonistic to the las QS system but were agonistic to the rhl …
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Design, synthesis, and biological activities of small molecules that target myotonic dystrophy
… including their synthesis and studies of their biological activity. The background of DM with a focus on its molecular mechanism and various therapeutic approaches are reviewed in Chapter 1. Chapter 2 includes the story of how simple ligands targeting CUGexp have been developed and …
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Design, synthesis, conformation and biological activities of cyclic alpha-melanotropin and related compounds.
… peptide from a 23 membered ring diminishes the biological effect of the peptide under testing.
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PROTEIN HYDROLYSATES FROM AGRICULTURAL WASTE BIOMASS: ENZYMATIC PREPARATION, BIOLOGICAL ACTIVITIES AND TECHNO-FUNCTIONAL PROPERTIES
… solubility, emulsifying and foaming capacity), biological and nutritional properties that are specific and distinct from those of the parent protein. PHs can be used (i) as biostimulants in horticulture due to their capacity to enhance crop quality parameters, nutrient efficiency and abiotic …
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Synthesis of pyrrolo[2,3-d]pyrimidines and pyrazino[2,3-d]pyrimidines and their biological activities
… were synthesised to investigate their biological activities to eventually produce potential new antifolates. Funtionalised nitroalkenes were successfully added to the C5 of 2-thioalkyl-6-amino-4-oxopyrimidines via a Michael reaction. Subsequent cyclisation was accomplished by a Nef …
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Synthesis and biological activities of [alpha]-aminoalkanephosphonic acids and [alpha]-aminoalkanephosphonous acids and their derivatives
A study of preparation methods for alpha-aminoalkanephosphonic, alpha-aminoalkanephosphonous and alpha-aminoalkanephosphinic acids has been made, based on the combined use of an aldehyde, an amino com pound, and a phosphorus reagent. Reported yields are frequently poor and the mechanisms of the …
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Discovery of novel highly selective Rho kinase (ROCK) inhibitory peptides and evaluation of their biological activities
… various protein kinase families. Finally, the activities of newly developed ROCK1 inhibitory peptide and its derivatives were evaluated in tissue- and organ bath- based models of heart failure, hypertension, PAH, myogenesis, and corneal neovascularization. Peptide25 and its derivative …
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Investigating the role that Interleukin-10's receptor binding properties play in defining its biological activities
… the molecular mechanisms underpinning IL-10’s activities.<br/><br/>IL-10 occurs naturally as a dimeric molecule which binds two receptor subunits: IL-10Rα and IL-10Rß. It has very poor affinity for the IL-10Rß receptor subunit and is unable to bind IL-10Rß in the absence of IL-10Rα (Walter, …
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The Chemical Analysis and Biological Activities of the Secondary Metabolites from Dalea mollis and Dalea albiflora
… prevent antimicrobial drugs from reaching their biological target, so the coordinated use of efflux pump inhibitors and antimicrobial drugs has been identified as a potential treatment for multidrug-resistant microorganisms. The secondary metabolites of <em>Dalea mollis </em>and <em>Dalea …
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Characterization, toxicity, and biological activities of organometallic compounds and peptide nucleic acids for potential use as antimicrobials
… of the ability to "tune" their chemical and biological properties by varying ligand attachments. Peptide nucleic acids, when linked to a cell-penetrating peptide (CPP), can suppress bacterial gene expression by an antisense mechanism and are attractive candidates for antimicrobial drugs …
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Characterization of the Biological Activities of Recombinant Fusion Protein Green Fluorescent Protein/Human Zona Pellucida Protein 3 (GFP/HZP3)
… the fusion protein displayed full spectrum biological activity of ZP3, and, most importantly unlike prior studies, this binding activity was elucidated in a direct way.</p>
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