Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 56 for “"Bioimaging and Biomedical Optics"”.
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Protein Loop Length Estimation From Medium Resolution Cryoem Images
… roles in virtually every biological process, and understanding their atomic structures is the key to unraveling how they carry out their work. Compared to the over half million protein sequences in UniProt, only around 25,000 unique sequences have been atomically modeled and deposited to PDB …
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Real-time Temperature Imaging Using Ultrasonic Change in Backscattered Energy
… to high-temperature ablation of tumors and unwanted electrical pathways has gained increased attention. Temperature imaging (TI) from magnetic resonance studies is the de facto standard for volumetric estimation of temperature. Ultrasound has the advantages of being cheap, portable, …
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Quantifying Magnetic Moments And Susceptibilities Of Small Cylindrical And Spherical Objects In Mri
… quantifying effective magnetic moments and susceptibility of either cylindrical or spherical-like small objects from magnetic resonance imaging (MRI). A standard 3D gradient echo sequence with only one echo time is intended for our approach to measure the effective magnetic moment of a …
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Identification of Human Adrenal Carcinoma Cells Using Photoacoustic Flow Cytometry
… with adrenal cancer, lack of early detection and diagnosis are an ever increasing problem in fighting the deadly disease. Currently, very few patients are diagnosed with adrenal cancer within the early stages due to the absence of symptoms until large tumors are formed, which is in most cases …
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Microcapsule Containing Lactic Acid Bacteria for Treatment of Peptic Ulcers
… to the intestinal mucosa (Lee, Lim, Teng, Ouwehand, Tuomola, & Salminen, 2000). While probiotics can be delivered to the infected areas in multiple fashions, microencapsulation is a newer form of delivering probiotics straight to the infected area. A whey protein microcapsule is thought to …
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Reconstruction Algorithms for Novel Joint Imaging Techniques in PET
… range of applications has made both research and industry combine it with other imaging modalities such as X-ray computed tomography (CT) or magnetic resonance imaging (MRI). The general purpose of this work is to study two cases in PET where the goal is to perform image reconstruction jointly …
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The Role Of Tissue Sound Speed As A Surrogate Marker Of Breast Density
… by using mammography, the current gold standard for breast imaging. There are many shortcomings to using mammography to measure breast density, including the use of ionizing radiation. Ultrasound tomography (UST) does not use ionizing radiation and can create tomographic breast sound speed …
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Design of x-ray source for real-time computed tomography
… the need for managing the high thermal loads demanded by real-time CT (30 acquisition frames per second). To add to the current field of knowledge, two x-ray tube concepts are presented in this dissertation. First, a simulation of transient thermal analysis was performed on a compact …
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Application Of Magnetic Resonance Imaging To Understanding The Pathogenesis Of The X-Linked Leukodystrophy Pelizaeus-Merzbacher Disease
… structure surrounding axons in both the CNS and PNS that facilitates nerve conduction. In the CNS, myelin is synthesized by oligodendrocytes, while in the PNS, myelin is synthesized by Schwann cells. In the CNS, Proteolipid protein 1 (PLP1), an integral membrane protein, is the major protein …
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Machine Learning Methods for Medical and Biological Image Computing
<p>Medical and biological imaging technologies provide valuable visualization information of structure and function for an organ from the level of individual molecules to the whole object. Brain is the most complex organ in body, and it increasingly attracts intense research attentions with the …
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Frequency Domain Ultrasound Waveform Tomography Breast Imaging
… high-resolution quantitative sound speed and attenuation maps of the breast can be created. In this thesis, we introduce some basic principles of imaging breast disease and the formalism of sound wave propagation. We present numerical methods to model acoustic wave propagation as well …
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Study of Immobilizing Cadmium Selenide Quantum Dots in Selected Polymers for Application in Peroxyoxalate Chemiluminescence Flow Injection Analysis
… (PI), polymethylmethacrylate (PMMA), and low-density polyethylene (LDPE). The combinations of QDs and polymer substrates were evaluated for their analytical fit-for-use in applicable immunoassays. Hydrogen peroxide standards were injected into the flow injection analyzer (FIA) …
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In Vivo Metabolic and Vascular Response to Hypoxia in Twist Knockdown Murine Breast Cancer
… transitions can lead to increased motility and invasiveness. It has also been linked to metabolic reprogramming and increased metastatic risk. Furthermore, metabolic preferences can increase proliferation, enhance metastatic potential, and influence the site of metastasis. We hypothesize …
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NEW ALGORITHMS FOR COMPRESSED SENSING OF MRI: WTWTS, DWTS, WDWTS
… as an argument for coefficient correlation and also considers the directionality of wavelet coefficients using Hybrid Directional Wavelets (HDW). Incorporating coefficient thresholding in both wavelet tree structure as well as directional wavelet tree structure, the experiments reveal higher …
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Multi-Frequency Processing for Lumen Enhancement with Wideband Intravascular Ultrasound
… scattering echoes may obscure the arterial lumen and make image interpretation difficult. Blood backscatter levels increase with transmission center frequency at a much greater rate compared to arterial tissue. These different frequency dependencies provide a potential method to distinguish blood …
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Understanding Radiation Resistance in Head and Neck Tumor Xenografts Using Diffuse Reflectance and Raman Spectroscopy
… 800,000 new patients are diagnosed with head and neck squamous cell carcinoma (HNSCC), a majority of whom are treated with a combination of daily fractions of radiation and weekly chemotherapy sessions for up to seven weeks. Current methods to evaluate treatment response of individual patients …
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Lesion identification and the effect of lesion on motor mapping after stroke
… most common cause of long-term severe disability and the motor system that is most commonly affected in stroke. One of the mechanisms that underlies recovery of motor deficits is reorganization or remapping of functional representations around the motor cortex. This mechanism has been shown in …
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Effect of hypoxia on spontaneous neural activity in the cortex of neonate mouse pups
… Hypoxia is known to occur in the human womb and exerts adverse effects on the developing fetus. Most of the ongoing research on hypoxia is performed on rodent brain slice taken from various brain regions using intracellular recording. Extensive work has been carried out to understand the …
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