Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 47 for “"Biodegradable polymers"”.
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Controlled drug release from oriented biodegradable polymers
… a novel method for controlling drug release from biodegradable polymers. The effect of various degrees of polymer orientation was studied in oriented Poly (L-lactic acid) (PLA) films containing curcumin and theophylline as model drugs. Additionally, direction specific drug release was studied from …
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The synthesis of biodegradable polymers using aluminium alkoxide initiators
… using a dialkoxide as an initiator yields polymers with molecular weights approximately half that of the corresponding reactions using a mono alkoxide. Transesterification reactions have also been found to occur after most of the monomer has been consumed. These transesterification …
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Modulation of cell morphology and function using synthetic biodegradable polymers
Synthetic biodegradable poly(DL-lactic-co-glycolic acid) (PLGA) has been fabricated into thin films for use as scaffolds for cell transplantation and guided tissue regeneration. We evaluated the ability of PLGA films to provide a suitable template for directing specific cell growth and tissue …
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Biodegradable polymers for the sustained release of antisense nucleic acids
… in a controlled manner to the site of action. Biodegradable polymer films and micro spheres were evaluated as delivery devices for the oligodeoxynucleotides and ribozymes. Polymers such as polylactide, polyglycolide, polyhydroxybutyrate and polyhydroxyvalerate were used due to their …
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Synthesis and evaluation of novel polymer modifiers for biodegradable polymers
The effects of ester plasticizers and copolymers on the mechanical properties of the natural biodegradable polymers, poly(3-hydroxybutyrate) [PHB] and poly(lactic acid) [PLA] have been studied after subjecting to melt processing conditions. Ester plasticizers were synthesized from citric, tartaric …
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Investigating Microbial Quorum Sensing Potential for Enhanced Production of Biodegradable Polymers
Polyhydroxyalkanoates (PHA) are a type of biopolymer that can be biosynthesised and accumulated by several specialised bacterial species. Their favourable mechanical properties coupled with their ability to naturally biodegrade within the environment make PHAs a potential candidate to replace …
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The Greener Alternative: Sustainable Development in Iron Catalysis and Biodegradable Polymers
… thermoplastic properties to naturally occurring polymers, we perform an esterification with palmitoyl chloride, a moiety of plamitic acid. Through reaction engineering improvements we increase yield, selectivity, recovery, and decrease process mass intensity (PMI) beyond what is known in the …
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Part I: Effect of Nanomicelle Size on Trans-scleral Permeability of Dexamethasone and Part II: Strategies to Minimize Octreotide Acylation during Sustained Release from Biodegradable Polymers
… characterized. Low molecular weight diblock co-polymers, mPEG₇₅₀-PCL₇₀₀ (DB1), mPEG₂₀₀₀-PCL₁₅₀₀ (DB2) and mPEG₅₀₀₀-PCL₄₀₀₀ (DB3) were synthesized by ring opening polymerization. Polymers were characterized by H¹ NMR (structure), gel permeation chromatography (molecular weights and …
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Characterization of Environmentally Friendly Polymers: Amylopectin and Its Blends
<p>Biodegradable polymers are desirable for a variety of applications, such as in packaging, agriculture, and medicine. Its biological degradation by microorganisms accelerated the interest in biodegradable polymers during the last decades. Within this group of innovative environmentally friendly …
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Novel PLA-based materials with improved thermomechanical properties and processability through control of morphology and stereochemistry. A study in improving toughness and processability of PLA by blending with biodegradable polymers and the two PLA enantiomers PLLA and PDLA to accelerate crystallinity and heat resistance
… derived from sustainable natural sources that is biodegradable and can be industrially composted. This material has been in the spotlight recently due to its sustainability and properties. However it has been invented in 1932 by Carothers and then patented by DuPont in 1954 (Standau et al. 2019). …
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Fabrication of hydroxyapatite-biodegradable polymer scaffolds by electrospinning for potential bone tissue application
… potential of combining hydroxyapatite (HA) and polymers to form synthetic composite materials used for bone tissue engineering applications. In this study, ceramic-biodegradable polymer composites are fabricated by electrospinning method. The biodegradable polymers used are poly(L-lactic acid) …
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Development and evaluation of a beta-glucan biopolymer formulation of lactoferrin produced using a novel cryomilling technique
… of protein degradation. Although synthetic biodegradable polymers have been extensively studied in the search for better protein delivery formulation development, the use of natural biodegradable polymers in drug delivery continues to be an area of active research. In the present study, a …
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Supercritical fluid spray processes for microencapsulation and formation of submicron aqueous dispersions of pharmaceutical compounds
… to produce larger, uniform particle sizes of biodegradable polymers. By suspending a protein in the solvent phase, the protein can be encapsulated/coated by the precipitating polymer. RESS is a process by which a homogeneous solution at supercritical conditions is sprayed through an expansion …
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The delivery of bioactive proteins using biodegradable microspheres
… microspheres were produced using a range of biodegradable polymers by single and double emulsion solvent evaporation and spray drying techniques. The proteins used in this study were mainly BSA, tetanus toxoid, F1 and V, Y. pestis subunit vaccines and the cytokine, interferon-gamma. The …
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Stability of proteins within biodegradable microspheres
In the past decade, biodegradable polymers have become the materials of choice for a variety of biomaterials applications. In particular, poly(lactic-co-glycolic acid) (PLGA) microspheres have been extensively studied for controlled-release protein delivery. However, significant issues arise in …
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Blends of Biodegradable Thermoplastics With Lignin Esters
Thermoplastic blends of several biodegradable polymers with lignin (L) and lignin esters were prepared by solvent casting and melt processing. Among the biodegradable thermoplastics were cellulose acetate butyrate (CAB), poly-hydroxybutyrate (PHB), poly-hydroxybutyrate-co-valerate (PHBV), and a …
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Development of simple 3D-printed scaffolds for liver tissue engineering
… of such geometrically complex scaffolds out of biodegradable polymers. These artificial tissues should maintain healthy, functional hepatocytes in proper contact with supporting cell types in the context of proper flow cues. This project comprises three major efforts. First, the design and …
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Biodegradable polymer/clay nanocomposites based on poly(butylene adipate-co-terephthalate) and Polylactide
… methodology which leads to property-enhanced biodegradable polymer products for broader application, as well as in promoting the use of bio-sourced renewable polymers such as Polylactide (PLA) in biodegradable polymers with desirable properties from petroleum based polymers such as PBAT, this …
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Fundamental Studies of Various Poly(L-lactide)/clay Nanocomposite Systems by in-situ Polymerization
Biodegradable plastics are a promising solution to the increasing global concern of persistent plastic wastes on the environment. In order for biodegradable polymers to successfully compete with commodity polymers, mechanical, thermal, and gas barrier properties must be improved. This can be …
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Biodegradation and Properties of Phosphated Polyurethanes
… increase. This along with the resistance of most polymers to degradation highlights the requirement of further investigation into effective methods of biodegradation, as well as into the synthesis of biodegradable polymers. Three standard polyurethanes with varying soft:hard segment ratios were …
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