Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Biodegradable nanoparticles"”.
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Development of novel diagnostics and therapeutics for amyotrophic lateral sclerosis
… axonal retrograde transport, 2) TTC-conjugated biodegradable nanoparticles, and 3) poly(glycerol-co-sebacate) acrylate (PGSA) and 3D scaffolds for human embryonic stem cell (hESC) and neuronal encapsulation.A Gd-TTC conjugate was developed and characterized that was shown to be highly visible …
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Synergistic development of an engineered biodegradable theranostic probe and lymph node organ-on-a-chip to study nanoparticle-lymphatic interactions
… nodes. Theranostic (therapeutic + diagnostic) nanoparticles have been used in a variety of applications, including the detection and treatment of cancer metastases in lymph nodes. However, accumulation in the liver remains a major concern with any nanoparticle-based intervention. We have …
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Design, Development and Evaluation of Dual Drug Nanomedicine for Non-Small Cell Lung Cancer
… Herein, dual loaded biocompatible and biodegradable nanoparticles (NPs) using Gemcitabine (Gem)a pyrimidine nucleoside antimetabolite and Gambogic acid (GA) (a highly hydrophobic chemo sensitizer agent)- were developed on human serum albumin-tannic acid nano-platform (HTA) for targeted …
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Synthesis and Characterization of Multi-Functional Nanoparticles for Therapeutic and Biosensing Applications
… drugs. The protein hormone release from biodegradable nanoparticles prepared using double emulsion solvent evaporation was quantified and release phases were identified. Insulin-like growth factor (IGF1)-loaded nanoparticles showed that the released protein was able to stimulate an …
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Biodegradable Polymeric Biomaterials in Different Forms for Long-acting Contraception and Drug Delivery to the Eye and Brain
… these limitations. In the recent decades, biodegradable polymeric drug delivery systems have emerged as promising candidates to solve the challenges of poor solubility, low permeability and sustained release owing to the advantages of biocompatibility, versatility, and tunable drug release. …
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SMART POLYMERIC DRUG NANOCARRIERS FOR BIOMEDICAL APPLICATIONS
Biodegradable polymeric nanoparticles (nps) have shown to be promising forms for the delivery of a wide array of drug formulations, because of their ability to: (i) increase the drug half-life in the blood stream, (ii) enhance the solubility of poorly-water soluble drugs, which represents the main …