Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 16 of 16 for “"Biocompatible polymer"”.
-
Layer-by-layer coated microneedles for cancer immunotherapy
… including protein or nucleic acid drugs and biocompatible polymer carriers, forming a 'sticky' layer-by-layer (LbL) film through electrostatic attraction. Past LbL MN strategies have all retained this 'sticky' nature and therefore require a long application time (15-90 mins) for drug …
-
Polymeric nanoparticle as a new platform for high removal of endotoxins from biopharmaceutical solutions
… demonstrated a cost-effective technology using a biocompatible polymer nanoparticle of approximately 800 nm diameter. The polymeric nanoparticle removed > 99% endotoxins from water, phosphate buffer saline (PBS) and protein solutions including monoclonal antibodies (MAb). It also showed a high …
-
Multifunctional fiber-based neural interfaces
… using thermal drawing process (TDP). All-polymer or hydrogel integrated probes with optical, electrical, and fluidic capabilities were developed all within the 100-200 [mu]m diameter, which allowed one-step surgery to the mouse brain and spinal cord for optogenetic experiments. This probe …
-
A novel osteochondral composite consisting of a self-assembling peptide hydrogel and 3D printed polycaprolactone scaffold : potential for articular cartilage repair
… chondrocyte division. PCL is a bioresorbable and biocompatible polymer scaffold, capable of supporting the attachment of both osteogenic and chondrogenic cells and cell-specific extracellular matrix production, that can be integrated with the peptide hydrogel to constitute an osteochondral …
-
Controlled release in inhalation
… The second experimental chapter introduces the biocompatible polymer chitosan (mw 190 – 310 kDa) to formulations containing leucine with findings of increased FPF with increasing leucine concentration (up to 82%) and the prolonged release of the active markers terbulataline sulfate (up to 2 …
-
MECHANICALLY ROBUST BIOCOMPATIBLE POLYMERIC NETWORKS FOR REPETITIVE LOADING
Crosslinked biocompatible polymer networks offer unique potential for biomedical applications that demand high resilience under repetitive load-bearing conditions. However, conventional hydrogels often exhibit poor mechanical strength and irreversible damage under cyclic deformation, while …
-
Multifunctional Graphene-Based Nanomaterials for Removal of Diverse Water Contaminants
… incorporating graphene-based nanomaterials into polymer matrices to create biocompatible polymer nanocomposites with multi-functional properties, enhancing the intended performance, making them reliable for future applications. The present cascade of studies aims to explore the properties of …
-
Poly(L-Lactic Acid) Langmuir Monolayers at the Air/Water Interface and Langmuir-Blodgett Films on Solid Substrates: Phase Behavior, Surface Morphology, and Crystallinity
… phenomena, the first such observation for a homopolymer Langmuir monolayer. Atomic force microscopy (AFM) images of PLLA LB-films prepared in the LC phase exhibit well-ordered lamellar structures. Molar mass scaling of lamellar dimensions, x-ray reflectivity, and reflection absorption infrared …
-
Deposition of Electroactive Polymers onto Polymer Nanofibers for Nerve Regeneration
… nerve tissue engineering. Electrospinning of the biocompatible polymer polycaprolactone (PCL) is used to produce porous and ordered nanofibers that resemble the structure and organization of the extracellular matrix, providing a suitable environment to promote the adhesion and directional growth …
-
Development of implantable devices for schizophrenia treatment
… poly(caprolactone) (PCL), a biodegradable and biocompatible polymer. In addition, PCL was also combined with poly(ethylene glycol) (PEG) 600, PEG 3000, and Tween® 80 in order to modify drug release profiles. The obtained implants were subsequently characterised. It was revealed that implants …
-
Direct-write assembly of 3D microperiodic scaffolds for tissue engineering applications
… methacrylate) (pHEMA) in a photopolymerizable solution, (2) a silk fibroin ink, regenerated from Bombyx mori silkworm cocoons, that can be induced to change conformation in a coagulating reservoir, and (3) a hydroxyapatite (HA) particle-filled silk fibroin ink. By carefully …
-
Crystallization of active pharmaceutical ingredients using microfluidic platforms and meniscus-guided coating
… thin films. Crystalline films were grown on a biocompatible polymer substrate and characterized by polarized optical microscopy to determine the film morphology and X-ray diffraction (powder and grazing incidence) to determine the molecular packing. Process parameters such as concentration of …
-
Study of Size Reduction, Reliability and Lead Safety of an Intra-Cochlear Lead-Zirconate-Titanate Micro-Actuator
… lead-free piezoelectric material, especially the biocompatible polymer PVDF, is first explored. An FEA is conducted to assess the feasibility of using PVDF as an alternative material for intra-cochlear micro-actuators. The FEA results indicate that PVDF cannot effectively drive the intra-cochlear …
-
Synthesis and Evaluation of Carbohydrate Based Cationic Polymers for siRNA Delivery and Tracking
Biocompatible and biodegradable macromolecules have been intensively used in pharmaceutical industries in various formulation preparations to fulfill different requirements. In the last two decades, RNA interference (RNAi) gene regulation has attracted a lot of attention for its high potency in …
-
Evaluation of Non-functionalized Single Walled Carbon Nanotubes Composites for Bone Tissue Engineering
… morbidity and quantity issues. The biodegradable polymer, Poly lactic-co-glycolic acid (PLAGA) was chosen because of its commercial availability, biocompatibility, non-immunogenicity, controlled degradation rate, and its ability to promote optimal cell growth. To improve the mechanical properties …
-
Effect of Encapsulated Species on Block Copolymer Micelle Self-Assembly
Due to their amphiphilic nature, block copolymers spontaneously form assemblies known as micelles in selective solvents. Minimization of the solution free energy drives the micellization process, with contributions from the polymer chains, surrounding solvent, and any additive molecules. Through …