Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"Biochip"”.
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Microfluidic biochip for optical detection of sepsis biomarkers from whole blood samples
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2024-09-16 without embargo terms
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Development and evaluation of a new biochip Nucleic Acid Test (NAT) multi-target for cervical cancer screening
… areas or populations. Recently, microarray biochip technology has been introduced into the clinical laboratory for HPV detection. One such test is the ProDect® CHIP HPV TYPING KIT (bcs Biotech Srl, Italy), which has the ability to identify 19 HPV types (all HR-HPV and most common LR-HPV …
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P450 biochips : development of a protein microarray platform for investigating cytochrome P450 clinical drug metabolism
… a novel cytochrome P450 array format, the P450 Biochip that allows quantitative and truly high-throughput measurement of cytochrome P450-mediated turnover reactions in sub-nanolitre volumes.
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FIELD-PROGRAMMABLE MICROFLUIDIC TEST PLATFORM FOR POINT-OF-CARE DIAGNOSTICS
… to perform microfluidic operations of the biochip. The FPLOC is the first EWOD biochip fabricated by the standard low-voltage complementary metal-oxide-semiconductor (CMOS) technology, which allows smooth on-chip integration of microfluidics and microelectronics. A total of 900 droplet …
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Surface plasmon-coupled emission for applications in biomedical diagnostics
… bioassay using a novel, disposable parabolic biochip. This biochip is designed to capture the light generated near the interface with high efficiency. The plasmonic structure is integrated into the chip by depositing a thin metal film on top of the recognition area and by carrying out …
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Entwicklung eines Biosensors zum Nachweis von Antibiotika und Sulfonamiden in Milch- Herstellung der immunchemischen Komponenten
… specificity. The sensitivities achieved on the biochip were well comparable with those obtained in the microtitre plate, whereas total assay time could be reduced to 15 min (microtitre plate) and 5 min (biochip), respectively.
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Mesoscale simulation of the photoresist process and hydrogel biosensor array platform indexed by shape
… fields in the 1980s led to the development of biochips in the 1990s. These devices enable rapid and simultaneous screening of a large number of biological analytes in a compact space, for a variety of applications. Cancer diagnosis through DNA typing, public water systems testing, and airline …
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Large core polymer optical backplanes for fluorescence detection
… utilizes the same polymer materials used for biochips to create optical components. By combining elements such as waveguides and mirror couplers, arrays of small devices capable of out-of-plane detection are possible, decoupling the biochip design from the transducer design while still …
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Preparation and characterization of functionalized surfaces for desorption-ionization mass spectrometry
… MALDI mass spectrometry-compatible proteolytic biochips and their application in structural proteomics. These functionalized surfaces allow both the cleavage of the studied protein and the MALDI matrix crystallization followed by a mass spectrometric analysis to be performed within a single …
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A novel genome-wide approach to identify in vivo targets of Notch signalling
… However, streptavidin chromatin pull-down (bioChIP) experiments from these tissues showed no significant enrichment of known Notch1 target sequences. A possible explanation could be the indirect and transient nature of the interaction between Notch, its DNA binding partner CSL and the …
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An electrical microcytometer for portable blood analysis in global health applications
… have been used to create a microfludic biochip, which uses electrical impedance sensing to analyze small sample volumes (~10 µL) of blood. The biochip progressively gains more functionality during the study. First, a chip was designed to confirm that the electrical impedance pulse …
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A Comprehensive Profiling of Hemostatic Activation and Thromboinflammatory Biomarkers and Cellular Indices in Predicting Outcomes in Venous Thromboembolism
… thromboinflammatory biomarkers using ELISA and biochip array. Statistical analysis included a descriptive test (median with IQR) and a comparative analysis (Chi square and Mann Whitney U tests). Prognostic analyses were performed using ROC curves and multivariate logistic regression analysis. …
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A microfluidic biosensor to electrically enumerate blood cells at point-of-care for infectious disease diagnosis and management
… We have counted CD4 and CD8 T cells from our biochip using healthy and HIV infected blood samples. The cell counts from the biochip are compared with those from the flow cytometer, showing the high correlation between the two techniques. We have also characterized the coincidence detection and …
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Novel anitbody-based assays for disease and food contaminant detection
… for subsequent incorporation into a disposable biochip senor. Naive and immune phage displayed libraries were also screened against a number of ampicillin conjugates for the isolation of an ampicillin-specific scFv.
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BIOMOLECULAR PRINTING FOR ARTIFICIAL LIFE-INSPIRED COMPARTMENTS AND SINGLE-CELL ARRAYS
… micropatterns for applications as biosensors and biochips. A novel approach based on inkjet printing has been exploited to pattern cell-adhesive biomaterials for single-cell harvesting and manipulation. The chip was realized by a novel green chemistry approach that combines polymeric layer …
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Applications of photolithographic techniques : materials modeling for double-exposure lithography and development of shape-encoded biosensor arrays
… ISTP and OTL materials for manufacturing. A new biochip platform named \Mesoscale Unaddressed Functional- ized Features INdexed by Shape" (MUFFINS) was developed in the Willson Research Group at the University of Texas at Austin as a potential method to achieve a new low-cost biosensor system. …
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Methylated DNA detection using a high-affinity methyl-CpG binding protein and photopolymerization-based amplification
… in 300 pm diameter spots on an inexpensive biochip without requiring bisulfite conversion. Sub-nanomolar concentrations (0.3 nM) of methylated DNA duplexes are detected using an MBD-GFP protein to transduce binding to either a fluorescent or colorimetric (visible hydrogel) signal formed by …
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Polyol- und Azlacton-Makromonomere für Netzwerksysteme, neue Werkstoffe und biomedizinische Anwendungen
… mit Azlactonen wurde zur Entwicklung eines Biochips zum Nachweis von hereditärer Hämochromatose genutzt.
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Advanced systems for the rapid detection of anthelmintic drugs in food
… limit (MRL) in liver matrix (100 μg kg-1).A biochip array was developed and validated to screen orange juice for fungicide and pesticide residues. The LOD for carbendazim (20 μg kg-1), 2-aminobenzimidazole (4.0 μg kg-1), thiabendazole (4.2 μg kg-1) and ivermectin (10.2 μg kg-1) residues were …
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THE ATTACHMENT AND CHARACTERIZATION OF DNA PROBES ON GaAs-BASED SEMICONDUCTOR SURFACES
… which is essential for high quality of biochip based on a DNA layer. Attachment of 8-base and 100-base thiolated ssDNA layers on arsenic terminated GaAs(001) was achieved and characterized. The covalent bonds between the thiolated oligonucleotides with As atoms on the GaAs surface were …
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