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Showing 1 to 20 of 170 for “"Biochemical analysis"”.
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BIOCHEMICAL ANALYSIS OF TWO DISTINCT METHIONYL-TRNA SYNTHETASES
Aminoacyl-tRNA synthetases (AARSs) are essential enzymes that catalyze the attachment of amino acids to their cognate tRNAs for protein biosynthesis at the ribosome. The long term objective of this project is to investigate catalytic features of methionyl-tRNA synthetase (MetRS) from two different …
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Biochemical Analysis of Evolutionary Divergent Vertebrate Larp6 Proteins
… maculatus) and human to carry out detailed biochemical analyses of vertebrate LARP6 RNA binding activity. The purpose is to determine if there is a species-specific protein-RNA interaction due to co- evolution of the ligand-binding surface within the LARP6 RRM and the RNA ligand sequence …
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Genetic and Biochemical Analysis of Murine Arylsulfatase C
Made available in DSpace on 2015-05-14T15:09:24Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 8009118.PDF: 4716091 bytes, checksum: 72b0c2bddf3ee033e07c86841a3925f8 (MD5) Previous issue date: 1979
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Genetic and Biochemical Analysis of Mouse Brain Gangliosides
Made available in DSpace on 2014-12-14T15:38:02Z (GMT). No. of bitstreams: 1 7709181.pdf: 4094753 bytes, checksum: 1df22f7b85743239dccb45e91e590e98 (MD5) Previous issue date: 1976
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The biochemical analysis of southern African rhinoceros populations
The drastic decline in the numbers of the five extant species of rhinoceroses world-wide, mainly as a result of poaching, have placed these species in imminent danger of extinction. This emphasizes the need to understand the relationships among the different species of rhinoceros. The advances in …
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Biochemical analysis of proteins in the telomere maintenance pathway
Eukaryotic linear chromosomes culminate in nucleoprotein structures designated telomeres. The terminal telomeric DNA consists of tandem repeats of a G-rich motif that is established and maintained by the action of the specialized reverse transcriptase called telomerase. In addition to the function …
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A Structural and Biochemical Analysis of the Drosophila Protein Period
… of various Drosophila PER fragments for biochemical and crystallographic analysis. Several stable PER fragments are identified, including one crystallizable fragment. The structure of the crystallized fragment is provided, and the implications of a critical intermolecular PER-PER …
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Biochemical Analysis of SNARE Protein Interactions – Role of Transmembrane Domain
SNARE (soluble NSF attachment protein receptor) Proteine umfassen verschiedene Familien von Proteinen, welche in Eukaryonten von der Hefe bis hin zum Menschen vorkommen. Sie sind für die Membranfusion bei zellulären Prozessen, wie Vesikeltransport, Neurotransmitterausschüttung oder …
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The genetic and biochemical analysis of Drosophila Wwox protein function.
… molecular functions of the Wwox protein. 2D-DIGE analysis was conducted on a number of different fly genotypes expressing differing levels of Wwox protein in both adult and embryonic flies. The proteomic changes resulting from lack of Wwox function as well as Wwox over-expression were detected …
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Genetic and biochemical analysis of the mammalian spindle assembly checkpoint
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Biology, 2001.
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GENETIC AND BIOCHEMICAL ANALYSIS OF TYPE 2 DIABETES AND DIABETIC COMPLICATIONS
… with T2D. It also explores a possible biochemical link between T2D and CVD.
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Genetic and biochemical analysis of a conserved DEAD-box helicase motif
… motif and establish a useful tool for in-depth analysis of conserved protein motifs
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Genetic and Biochemical Analysis of Phosphinothricin Tripeptide Biosynthesis in Streptomyces Viridochromogenes
Our investigations led to the discovery of new biosynthetic intermediates and revealed inaccuracies in the previously published pathway. Specifically, this thesis work established that step III of PTT biosynthesis is the reduction of phosphonoacetaldehyde to hydroxyethylphosphonate by PhpC, an …
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A genetic and biochemical analysis of the bacteriophage [lambda] cro protein
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1988.
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Biochemical analysis of the interaction between transfer ribonucleic acid and exportin-t
… of tRNA•exportin-t•Ran•GTP was studied by biochemical and biophysical methods. Firstly, photocrosslinking was used to determine the contact sites between tRNA and exportin-t. 4-Thiouridine (s4U) was introduced into tRNAPheT.th by in vitro transcription with T7 RNA polymerase and crosslinked …
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Genetic and Biochemical Analysis of the Bryan Strain of Rous Sarcoma Virus
… unconserved. Restriction enzyme mapping analysis showed the structure of the BH-RSV alpha pol gene to be basically unchanged from that of BH-RSV beta. Using cloned DNAs, we have constructeds molecular clones in which the pol gene of non-defective RSV was replaced with the pol gene of …
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Structural characterization and biochemical analysis of ID2, an inhibitor of DNA binding
… structures. Key residues based on the structural analysis of ID2 were identified and mutated to gauge their importance in the dimerization of the ID protein family through competitive electrophoretic mobility shift assays.
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Genetic and Biochemical Analysis of Methyltransferase Gene Regulation in Methanosarcina Acetivorans C2A
… operons in M. acetivorans C2A as a model. Mutant analysis established that these operons encode bona fide methanol MT1s, which have distinct roles in methanol utilization. These enzymes might have different biochemical properties and their expression might therefore be regulated in response to …
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Genomic and biochemical analysis of oxidative stress in birds with diverse longevities
… of experimental and in silico tools for genome analysis to screen selected regions of the chicken (Gallus gallus) mitochondrial genome (mtGenome) for SNPs. A total of 113 SNPs was identified which formed 17 haplotypes. The length of the turkey mtGenome sequence developed was 16,967 bp in length, …
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