Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 783 for “"Bioavailability"”.
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Bioavailability of Bioactive Compounds
… which compounds have high efficacy as well as bioavailability. The ability of a compound to exert its health promoting effects depends on its bioavailable dose, rather than the administered dose. The present study aimed to evaluate the stability of Ara-1 and Ara-3 under cell incubation …
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Statistical aspects of bioavailability
… aspects associated with (i) measuring the bioavailability of a drug (Chapter 2) (ii) establishing the equivalence of a new and standard formulation of a drug (Chapter 3). In the process of reviewing the literature two problems were identified. Firstly, it is commonly assumed that …
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Bioavailability of sediment-sorbed fluorene
The bioavailability of sorbed organic chemicals is a major concern in the application of bioremediation processes to contaminated sediments. Sorption of pollutants may lead to the inability of microbes to come in contact with the compound. Studies presented herein investigate the biodegradation and …
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Nitric Oxide Bioavailability Regulation by Hemoglobin
Nitric Oxide (NO) is a diatomic molecule with one unpaired electron which makes it highly reactive. Because of its small size it can diffuse rapidly through body tissues. These characteristics allow NO to function very well as local signal transductor. NO plays an important role in the dilation of …
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Bioavailability studies of folate in humans.
Bioavailability studies of folate in humans.
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Bioavailability of organic contaminants in sediments.
The bioavailability of polycyclic aromatic hydrocarbons (PAHs) and chlorobiphenyls (CBs) in sediments is largely dependent on the freely dissolved concentration of these pollutants. However, measuring these is challenging, due to the low concentrations of lipophilic contaminants in the environment …
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Improving sulforaphane bioavailability from cooked broccoli
… ways to improve SF formation and absorption (bioavailability) from CB, through better understanding the mechanism. Our first hypothesis was that frequent intake of CB would enrich the bacteria that contain myrosinase-like activity, therefore enhancing SF bioavailability and bioactivity. Our …
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Nanocarriers for drug targeting and improved bioavailability
… water solubility and consequently by a low oral bioavailability. Different nanocrystals orally disintegrating tablets (ODT) were prepared to enhance piroxicam dissolution velocity and saturation solubility. Nanosuspensions were prepared using high pressure homogenization technique. Different ODT …
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Bioavailability of dissolved organic matter in coastal waters
… this study the seasonal variation in bioavailability of DOM was quantified in two contrasting marine systems: Loch Creran (Scotland) and the Ría de Vigo (Spain). The bioavailable DOM (BDOM) varied temporally at both stations and controlled the seasonal variations in DOM. Dissolved …
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Diversified strategies for improving iron bioavailability of maize
… prone to iron deficiency because of the low iron bioavailability (FeBA). The overall objective of this three-part study is to enhance FeBA in foods made of maize through novel fortification techniques, processing modifications, and genetic modifications.;The first study focused on the …
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Intestinal Uptake of Carotenoids: Implications for Carotenoid Bioavailability
Lycopene is the predominant carotenoid in tomatoes and tomato-based foods and is also a predominant carotenoid in human serum and tissues. The observation that serum and tissue lycopene is more than 50% cis-lycopene, whereas tomatoes and tomato-based foods contain mainly all-trans lycopene, has led …
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Bioavailability of Calcium and Zinc in Soy Products
… and monitoring of the processing conditions. Bioavailability studies involved feeding soy product-based diets to weanling or young rats for 3 (zinc studies) or 4 weeks (calcium studies). Calcium (Ca) availability was determi
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Iron bioavailability from diets containing intact fiber sources
… were conducted with chicks to estimate the bioavailability of Fe from high fiber foods and feeds and determine if specific components of fiber affected Fe bioavailability. The effects of high fiber food and feeds on supplemental Fe bioavailability also were assessed.
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Prediction of Metabolic Stability and Bioavailability with Bioisosteric Replacements
… the metabolic stability of structures and their bioavailability. Coralie Atom-based Statistical SOM Identifier (CASSI) is a site of metabolism (SOM) predictor which provides a SOM prediction based on statistical information gathered about previously seen atoms present in similar environments. …
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Bioavailability of phosphorus from various sources for young turkeys
… were conducted to determine the relative bioavailability of various phosphate products with an emphasis on the defluorinated phosphates. In Series I, phosphorus in commercial mono/dicalcium phosphates, commercial dicalcium phosphates, commercial defluorinated phosphates, and experimental …
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Improving estimations of phosphorus bioavailability for lactating dairy cows
Phosphorus (P) is an instrumental nutrient in numerous physiological processes, but can have detrimental environmental impact if fed in excess. Increased P intake in dairy cows leads to increased fecal excretion of P and a reduction in efficiency of use. Variability in P concentration or …
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Transporter-Targeted Prodrug Delivery to Improve Oral Bioavailability of Saquinavir
… and fast biotransformation lead to its poor oral bioavailability and limited therapeutic efficacy. The objective of this dissertation project is to investigate whether stereoisomerized peptide prodrugs targeting influx transporter system could improve intestinal absorption and oral bioavailability …
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