Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Bioadhesion"”.
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Bioadhesion to model thermally responsive surfaces
This dissertation focuses on the characterization of two surfaces: mixed self-assembled monolayers (SAMs) of hexa(ethylene glycol) and alkyl thiolates (mixed SAM) and poly(N-isopropylacrylamide) (PNIPAAm). The synthesis of hexa(ethylene gylcol) alkyl thiol (C11EG6OH) is presented along with the …
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Tissue-material interactions : bioadhesion and tissue response
Diverse interactions between soft tissues and implanted biomaterials directly influence the success or failure of therapeutic interventions. The nature and extent of these interactions strongly depend on both the tissue and material in question and can presumably be characterized for any given …
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High-throughput platforms for investigating bioadhesion and cell migration
… the efficacy of thermally controlled, reversible bioadhesion. I also used these large format gradients to generate shallow immobilized protein gradients to investigate the effect of ligand density on cell adhesion and migration. The results showed the utility of these large format gradients for …
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Formulation studies on cysteamine for the treatment of nephropathic cystinosis.
… gel network was formed at low shear stress, the bioadhesion of the gel was increased with inclusion of a cysteamine derivative (e.g. mean force of 0.067N compared to 0.107N, with compound included) and eight-hour, first-order release from the gel was observed. There was significant adhesion …
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Exploring the Interface Between Macroorganisms and Microorganisms: Biochemical, Ecological, and Evolutionary Contexts
… and glue curing, both central to understanding bioadhesion. The work on fiddler crabs and blue crabs contributes to our understanding of chemoreception of feeding and reproductive behaviors.</p><p>The work presented here highlights how biological secretions from macroorganisms serve multifaceted …
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Weak polyacid brushes : synthesis, swelling behavior, complex formation and micropatterning
… of biological processes such as signaling, bioadhesion or the stabilization of micelles as in many biological systems (surface) biopolymers adopt constrained conformations similar to those of polymer brushes and a mix of different ions is usually present. Moreover, an understanding of the …
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Controlling Microbial Adhesion to the Surfaces Using Topographical Cues
The state of adhesion of bacteria to nanofiber-textured model surfaces is analyzed at single-cell level. The results reveal similarities between the effect of topography on bacteria-surface interactions and vesicle-surface interactions. The results are discussed in the context of controlling …
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Development and Evaluation Of HIV gp120 Responsive Microbicide Formulation for the Prevention of HIV Sexual Transmission
… gp120 sensitivity (≤ 100 µg/ml). Furthermore, bioadhesion studies, performed ex vivo on porcine vaginal tissue, demonstrated that FITC−𝐶+𝑀𝑅𝑃 adheres to vaginal tissue at levels varying between 10% ± 1 and 20% ± 2, depending on the number of Con A layers in the formulation. In chapter 6, 𝐶+𝑀𝑅𝑃 …
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Nanostructures for protection and vehiculation of bioactive molecules
… friendly toward biological membranes and favor bioadhesion. The physico-chemical characterization of structure and stability of three different lipid based formulations intended for drug delivery is the central issue in this thesis. The main contents here discussed are outlined as follows. …