Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"BioID2"”.
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Identification of the TPC2 interactome reveals TSPAN10 and OCA7 as key players in the biogenesis of melanosomes
… cation channel, TPC2, genetically fused with the BioID2 biotin ligase, to identify proteins in proximity to TPC2 at the cytosolic surface of melanosome membranes of MNT1 melanoma cells. Through mass spectrometry analysis of biotinylated proteins enriched through Streptactin pulldown, a TPC2 …
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Study of the intracellular trafficking of the pre-T-cell receptor and its role in T-cell lineage commitment
T-cell development is a complex multi-step process, driving the maturation of hematopoietic stem cells into fully functional mature T-cells that play a major role in the adaptive immune response against pathogens. This developmental process is regulated by a series of checkpoints in which the …