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Showing 1 to 2 of 2 for “"Biliary morphogenesis"”.
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A THREE DIMENSIONAL MODEL OF HUMAN HEPATO-BILIARY ORGANOGENESIS
… formed bile duct structures by undergoing biliary morphogenesis process and attained apicobasal polarity in the organoids. The duct morphogenesis process was interrupted by inhibiting Notch signaling, thus creating a liver developmental disease model exhibiting a phenotype similar to …
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Dissecting combinatorial microenvironmental regulation of cell fate and function using a multi-modal arraying platform
… roles in differentiation towards a biliary epithelial cell fate. Parallel TFM measurements in arrayed microenvironments indicated that progenitor cell differentiation towards biliary fates is a coordinated function of ECM composition, substrate stiffness, and cell contractility. …