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Showing 1 to 20 of 36 for “"Bile Salts"”.
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Characterizing Interfacial and Bulk Interactions Between Cellulose Ethers and Bile Salts: Impact on In Vitro Lipid Digestion
… of lipids in the human intestinal tract. Since bile salts (BS) play key roles during this process, lipid digestion could be controlled ultimately by limiting the access of BS to the lipid surface. Cellulose ethers (CEs), surface-active dietary fibers and common food additives, might be promising …
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Polymer-bile salts interaction and its impact on the solubilisation and intestinal uptake of poorly water-soluble drugs
I would like to thank my primary supervisor Dr. Sheng Qi for the invaluable support and encouragement received during my PhD time at UEA. Thanks also to my supervisors Prof. Peter Wilde and Prof. Duncan Craig for their help. I would also like to express my gratitude to Prof. Pete Belton, Dr. …
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Quasielastic light scattering studies of the formation of micelles of human apolipoproteins A-I and A-II, lecithins and bile salts
Thesis (Ph.D.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1984.
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Characterizing induced gene expression in Shigella flexneri following bile salt exposure
… Shigella utilizes host physiology, specifically bile salts as signals for invasion and virulence gene expression. This study aimed to build upon previous research analyzing the bile salts transcriptional profile of Shigella flexneri 2457T, in which an induction of the uncharacterized gene was …
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Role of dry beans (Phaseolus vulgaris L.) in binding bile salts and modulating lipid digestion: Impact of the bean matrix and high-hydrostatic pressure processing
… (e.g. viscosity) of DF, and involve binding to bile salts (BS) in the small intestinal to prevent BS re-absorption which further promote cholesterol catabolism and delay lipid digestion. Nevertheless, the precise mechanisms are not fully understood yet. In addition, cooking and processing …
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Resistance to antimicrobial agents in bifidobacteria
… with inhibitory host-produced substances such as bile salts. Another aspect which should be studied is the safety of the probiotic bacterium and risks of acquisition of genes for resistance to antimicrobial agents. Although bifidobacteria exhibit resistance to a wide range of antibiotics, little …
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Tale of Two Hosts: Vibrio parahaemolyticus Toxicity Against Human and Shrimp
Bile is an important component of the human gastrointestinal tract with an essential role in food absorption and antimicrobial activities. Enteric bacterial pathogens have developed strategies to sense bile as an environmental cue to regulate virulence genes during infection. We discovered that …
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Tale of Two Hosts: Vibrio parahaemolyticus Toxicity Against Human and Shrimp
Bile is an important component of the human gastrointestinal tract with an essential role in food absorption and antimicrobial activities. Enteric bacterial pathogens have developed strategies to sense bile as an environmental cue to regulate virulence genes during infection. We discovered that …
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Strain identification, viability and probiotics properties of lactobacillus Casei
… Lactobacillus strains in the presence of acid, bile salts and the or bile salt deconjugation, 3) to investigate viability of freeze dried Lactobacillus strains at various temperature during storage and their proteolytic activity, 4) to investigate the growth, viability and activity of …
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NMR Studies on Model Membranes. Interaction with Metal Ions, Ionophores and General Anaesthetics
… transport induced by alamethicin 30, A23187, bile salts and phospholipase A was investigated by following time dependent changes in the 1H-NMR spectrum of phospholipid vesicles. The mechanisms involved in the permeability induced by the bile salts and phospholipase was shown to be critical …
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Evaluation of bacterial polymers as protective agents for sensitive probiotic bacteria
… exposure to simulated intestinal juices and bile salts. The antibacterial property of Bifidobacterium strains was also investigated against four pathogenic bacteria. γ-PGA, a naturally occurring biopolymer was produced by two bacteria (Bacillus subtilis ATCC 15245 and B. licheniformis ATCC …
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Gut microbiota-mediated bile acid metabolism: implications for oral drug absorption
… investigates a potential mechanism, ‘microbial bile acid metabolism’, by which the intricate interplay between the host and gut bacteria may affect the pre-absorption behaviour and uptake of orally administered drugs. Bile salts have long been appreciated within the pharmaceutical field to be …
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Absorption of Chromium Across the Rat Small Intestine
… of increased concentration of hydrogen ions. Bile salts and E.D.T.A. did not affect the serosal transport of chromium, however, the interaction of chromium with citric acid increased the amount of chromium transported to the serosal compartment. There was strong and tenacious interaction …
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Characterization and encapsulation of probiotic bacteria using a Pea-protein Alginate matrix
… were able to survive 5 h exposure to 0.3% Oxgall bile at pH 5.8. The relative ranking of probiotic adherence to Caco-2 cells was determined to be: L. acidophilus > B. catenulatum > B. adolescentis > B. infantis, which correlated with 4.5 104, 3.1 103, 2.6 101, and 1.5 101 cfu/mL associated with …
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THE ANALYSIS OF CHEMICALS AND BIOCHEMICALS BY HIGH PERFORMANCE CAPILLARY ELECTROPHORESIS
… the separation of the steroids, the addition of bile salts into the electrophoretic medium was found to provide enhanced resolution. Quantitation of antibiotics and steroids in commercial samples were performed using the optimum separation conditions. In the case of the plant growth regulators, …
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Potensi Lactobacillus plantarum sebagai probiotik secara in vitro: kajian ketahanan terhadap asam, garam empedu dan penghambatan terhadap bakteri patogen.
… vitro testing of the study resistance to acids, bile salts 0.3% (w/v) and inhibition of pathogenic bacteria, namely Staphylococcus aureus, Escherechia coli and Salmonella thypi. Data obtained from this study were analyzed descriptively. The results showed that as pH increased the number of …
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Characterization of probiotic Lactobacillus spp. isolates from commercial fermented milks
… and the combined effects of pH, enzymes and bile salts on survival of tested isolates was tested. The tested isolates were able to survive at low pH environment and also high concentrations of bile salts of the upper digestive tract. The potential of tested isolates for biofilm formation was …
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Investigating the Effects of Glycochenodeoxycholic Acid on Mutant Murine Norovirus P-Domain Structure and Antibody Interactions
… promote infection. NoVs contain 90 highly mobile P-domain dimers across their capsid surface with specific P-domain conformations known to facilitate host cell infection and promote immunological evasion. To understand these mechanisms, we investigated a novel murine norovirus (MNV) mutant …
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Development of a mucosal vaccine delivery system
… with and without the incorporation of bile salts were formulated by novel preparation methods in order to provide suitable immunogen carriers for delivery to mucosal surfaces. The nanoparticles were physically characterised by determination of size, zeta potential, and morphological …
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The gastrointestinal effects of calcitonin and related peptides
… pentagastrin in the presence of indomethacin or bile salts. A calcitonin-stimulated increase in bicarbonate secretion may be suggested to explain these results. A mechanism for the gastrointestinal action of calcitonin is postulated.
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