Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 68 for “"Betaine"”.
-
The Role of Potassium in Betaine-Homocysteine Methyltransferase
… of Hcy to methionine: methionine synthase and betaine-homocysteine methyltransferase (BHMT). Methionine synthase function depends on adequate availability of vitamin B12 and folate which links cardiovascular disease risk to nutritional status. The Hcy remethylation pathway through BHMT, …
-
Interrelationships Among Sulfur Amino Acids, Choline and Betaine in the Chicken: Effects on Betaine-Homocysteine Methyltransferase Activity, Homocysteine Utilization and Choline Bioavailability
… diet responded to choline, but not methionine or betaine. In Assay 1, weight gain of chicks increased linearly $(P<0.01)$ with increasing concentrations of choline from choline chloride, FL or DL. Multiple linear regression analysis indicated bioavailable choline concentrations of 2.0 and 3.5% for …
-
Role of Betaine-Homocysteine S-Methyltransferase in Homocysteine Methylation
… (74, 50 and 46%, respectively). Increased plasma betaine (1465%) confirmed that BHMT was functionally inhibited in vivo. Interestingly, liver CBS activity and protein levels decreased (56 and 26%, respectively). To assess whether BHMT inhibition affected glutathione levels and/or caused fatty …
-
Developmental and evolutionary analysis of betaine homocysteine methyltransferase genes
… because mammals cannot synthesize homocysteine. Betaine-homocysteine methyltransferase (BHMT) and BHMT-2 methylate homocysteine to form methionine using betaine and S-methylmethionine, respectively. Betaine is produced de novo from choline and is also found in the diet, whereas S-methylmethionine …
-
The Effect of Betaine Supplementation on Performance and Muscle Mechanisms
… </strong>Recent research has shown that betaine supplementation can increase strength and power performance. To further investigate the ergogenic effects of betaine supplementation a balanced, randomized, double-blind, repeated measures crossover study was designed to examine select …
-
Betaine-Homocysteine Methyltransferase: Tissue Distribution, Nutrient Regulation, Genomic Organization, and Promoter Isolation
… were estimated to be 2160 muM and <10 muM for betaine and L-Homocysteine, respectively. These constants were same as the published human liver BHMT constants. Thus, we conclude that kidney and liver BHMT proteins are the product of one human BHMT gene.
-
New Insights Into the Structure and Function of Betaine-Homocysteine S-Methyltransferase
… intermediate of methionine metabolism. Betaine-homocysteine S-methyltransferase (BHMT) is one of two enzymes capable of remethylating Hcy to methionine. We report that BHMT is susceptible to conformation-dependent oxidative inactivation. Two oxidants, methyl methanethiosulfonate (MMTS) …
-
Mechanisms into the development of fatty liver disease: role of bile acids, Betaine and MHY908
… therapies for NAFLD such as bile acids, betaine and a PPARα/γ dual agonist MHY908. Method: Human hepatoma cell line, VL17A cells were treated with saturated fatty acid palmitic acid (PA) with a range of concentrations between 10 μM - 300 μM for 24 h, 48 h and 72 h after which lipid …
-
The Effect of High Salt Intake on Betaine-Homocysteine S-Methyltransferase Expression in the Guinea Pig
BHMT is the only enzyme known to metabolize betaine, leading to the hypothesis that BHMT is down-regulated under conditions requiring the accumulation of betaine, such as high salt intake. BHMT is expressed in the livers of mammals and only a few species such as pig, guinea pig, and primates …
-
Recombinant Human Betaine -Homocysteine S -Methyltransferase: Discovery as a Zinc Metalloenzyme, and Regulation of Activity by Redox Status
The lack of activity in the absence of reducing agent is not due to loss of Zn at the catalytic site. When reducing agent-free preparations of 5Cys/Ala are incubated with the Zn chelator, PAR, and the absorbence of the Zn-PAR chelate is monitored, there is no change in absorbence unless …
-
Kinetic characterization of methyl donor substrates and inhibitors of human, pig, and rat liver betaine homocysteine S-methyltransferase (BHMT)
This Thesis was approved for publication on 2015-05-01 at 08:42.
-
An investigation of the use of exogenous Glycine Betaine and Seaweed Extract to ameliorate drought stress in cutting propagation of Griselinia littoralis and Lavatera x Clementii
The exogenous application of Glycine Betaine (GB) and seaweed extract (SWE) has been suggested as a possibly effective approach for improving the drought tolerance of cuttings. The aim of this study were to test the feasibility of GB and GB+SWE helping cuttings fight drought stress during cutting …
-
Cloning, Heterologous Expression, and Characterization of Human and Escherichia Coli Choline Dehydrogenases
… the first committed step of choline oxidation to betaine-glycine in mammals and in some bacteria such as E. coli and P. aeruginosa . In mammals, it is an important source of one-carbon units for cytosolic folate- and AdoMet-dependent reactions, while in E. coli, betaine-glycine, the final product …
-
Molecular characterisation of the mechanisms of compatible solute accumulation in Listeria monocytogenes
… physiological investigations identified glycine betaine, carnitine, and proline as the principal compatible solutes in the listerial osmostress response, genetic alanysis of the uptake/synthesis systems governing the accumulation of these compounds has, until now, remained largely unexplored. …
-
Metabolic differentiation in the lichen Cladonia portentosa from different wet nitrogen deposition regimes’
… with PCA and PLSR allowed the identification of betaine lipids (BL) as potential biomarkers of nitrogen enrichment.<br/>A compound tentatively identified as monoacylglycerol-(N,N,N trimethyl)-<br/>homoserine (MGTS) showed the strongest positive relation to increasing wet<br/>nitrogen deposition …
-
Investigação de redução da cristalinidade da celulose sob a influência de diferentes misturas eutéticas.
… glycerol/potassium carbonate and glycerol/betaine, over a period of 4 h at a temperature of 80ºC and molar ratios of 5:1 and 10:1. The celluloses obtained in the procedure were analyzed using various techniques, such as: Fourier transform infrared spectroscopy (FTIR), X-ray diffraction …
-
Analysis of plant analytes using capillary electrophoresis and high performance liquid chromatography
… very common osmoregulants (proline, glycine betaine and mannitol). A diverse array of methods has been reported for determining each of these analytes, however, the literature on osmoregulants and their analysis is quite disjointed and traverses both biological and chemistry fields. …
-
The synthesis and characterisation of Langmuir-Blodgett film forming TCNQ adducts.
… number of N-alkylpyridinium benzimidazolate betaine derivatives and the related betaine-TCNQ adducts were prepared and their LB film forming properties were studied.
-
Effects of dietary feed additives on the performance and gastrointestinal health of broilers exposed with coccidial spores and varying litter conditions
… additives, essential oils (garlic and cinnamon), betaine, butyrate, and benzoic acid, on broilers raised under coccidial challenges and varying litter conditions such as differences in moisture content and reuse of litter, focusing on their potential to improve performance, gastrointestinal …
-
Effect of carbohydrate degradation upon browning and corrosion in canned applesauce
… and browning in canned applesauce. 2. Betaine appears to be an efficient corrosion inhibitor, reducing corrosion without excessively increasing overall browning. 3. Lecithin appears to be a better corrosion inhibitor than betaine. However, this advantage is negated by its greater …
Page 1 of 4