Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 40 for “"Beta-oxidation"”.
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Beta-Oxidation of Elaidic Acid by Heart Mitochondria
Made available in DSpace on 2015-05-13T15:26:59Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7915380.PDF: 3671512 bytes, checksum: db04dbdd7eb2fdfe6625d6fa2c5d4560 (MD5) Previous issue date: 1979
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Peroxisomal beta-oxidation of fatty acids in neonatal swine
… a limited capacity for hepatic mitochondrial $\beta$-oxidation in piglets, as well as their high rate of mortality, prompted a series of studies to examine development, importance, nutritional regulation, and inducibility of peroxisomal $\beta$-oxidation (POX) of fatty acids in piglets. POX …
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Hepatic lipid metabolism and peroxisomal beta-oxidation in dairy cows
… were conducted to measure peroxisomal $\beta$-oxidation in the liver of cows and to determine the effects of physiological state and source of dietary energy (carbohydrate or lipid) on liver metabolism, blood metabolites, and production variables.
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The effect of beta-oxidation or TCA cycle inhibition on mitochondrial function and the sensitivity of high resolution respiratory detection
INTRODUCTION: A dysfunction in fatty acid beta-oxidation (β-oxidation), particularly medium chain acyl-CoA dehydrogenase (MCAD) dysfunction is a major cause of mortality and its diagnosis is usually achieved by measuring specific protein activities or metabolites in blood and/or urine samples. …
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Metabolism of Gallic Acid by Eubacterium Oxidoreducens
… both NADP-linked. These results suggest that the oxidation of formate or H$\sb2$ may be indirectly linked to the reduction of phloroglucinol. A dihydrophloroglucinolase was present, which hydrolyzed dihydrophloroglucinol to 3-hydroxy-5-oxohexanoate. This six-carbon ring cleavage product presumably …
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Bioenergetik und Biochemie bei zerebralen Organoazidopathien am Beispiel der Glutaryl-CoA-Dehydrogenase-Defizienz und der Succinat-Semialdehyd-Dehydrogenase-Defizienz
… Enzymaktivitäten der Atmungskette und der beta-Oxidation in Gewebehomogenaten von Gcdh- und Ssadh-defizienten Mäusen bestimmt. An isolierten Enzymen, Gewebehomogenaten und submitochondrialen Partikeln wurde der Einfluss der akkumulierenden Metabolite auf die Enzyme der Atmungskette, der …
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Effects of maturation, polyploidy, and nutrition on growth, composition, and gene expression within fatty acid metabolism in rainbow trout
… data indicate 2N fish have increased fatty acid beta-oxidation in white muscle that was associated with altered gene expression within the mTOR pathway and in visceral adipose tissue that was associated with increasedpparbeta expression. In contrast, increased expression of genes involved in …
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PaaG and PaaF: New Members of the Crotonase Superfamily
… by enzyme assays using purified proteins that beta-oxidation in phenylacetate metabolism proceeds via adipyl-CoA intermediates. I showed that PaaG catalyzes the isomerization of trans-Delta 3-hexenedioyl-CoA to trans-Delta2-hexenedioyl-CoA, uses an Asp as a general base, and the reaction …
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Identification and Characterization of Ethanol Responsive Genes in Acute Ethanol Behaviors in Caenorhabditis elegans
… that activates fatty acids for mitochondrial beta-oxidation. Animals carrying mutant acs-2 have significantly reduced AFT and we explored the role of genes in the mitochondria beta-oxidation pathway for alterations in ethanol responsive behaviors. We have shown that knockdown of ech-6, an …
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Fatty Acid Degradation in Escherichia Coli and Salmonella Enterica Serovar Typhimurium
… were responsible for the greater efficiency of beta-oxidation.
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Pathological features of mitochondrial respiratory chain dysfunction
… and long-chain fatty acid catabolism by the beta oxidation pathway. Given the role of mitochondria in maintaining cellular physiology, mitochondrial dysfunction often leads to disease. One major class of mitochondrial pathologies is caused by defects in the mitochondrial respiratory chain …
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Effect of the ligands of thyroid hormone receptor on non-alcoholic fatty liver disease
… mitochondrial and peroxisomal fatty acid beta-oxidation. To investigate whether T3 could also reverse fully established fatty liver, rats were fed the CMD diet for 10 weeks and then cofed T3 for 1 week. Coadministration of T3 resulted in a complete regression of liver steatosis associated …
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Phosphorylation of Skeletal Muscle Acetyl-CoA Carboxylase by AMPK Enhances Palmitoyl-CoA Inhibition
… controls the rate of fatty acid metabolism. ACC beta or 2 has been shown to be localized on the mitochondria in close proximity to carnintine palmitoyl transferase 1 (CPT-1), the enzyme responsible for the influx of acyl-CoA into the matrix where beta oxidation takes place. CPT-1 is inhibited by …
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Identification of new genes and pathways that act to delay C. elegans aging
… a ketoacyl thiolase involved in fatty acid beta-oxidation, suggesting that defects in fat metabolism can affect the regulation of aging.
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Conjugated linoleic acid isomers anti-neuroinflammatory effects on activated microglial cells
… involved in the anti-inflammatory peroxisomal beta-oxidation pathway that effectively processes CLA isomers. Importantly, t10,c12-CLA markedly inhibited stearoyl-CoA desaturase 1, which influenced the production of monounsaturated fatty acids. The profile of NAEs was significantly modified by …
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Epigenetic toxicity of PFOA in HepG2 cells and its role in lipid metabolism
… are also changed, especially those regarding beta-oxidation pathway and lipid synthesis. Global methylation level of HepG2 cells was found to be in overall inverse proportion with different dosages of PFOA and had corresponding trends with mRNA expression of most genes of interest. Lipid …
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Uncoupling Lipid Metabolism from Inflammation in Adipose Tissue
… to suppressed inflammation, increased beta-oxidation, and improved mitochondrial function in FABP4 deficient macrophages. Interestingly, the FABP4-UCP2 axis also extends to a human bariatric surgery model. In the subcutaneous adipose tissue from patients undergoing bariatric surgery, …
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Study of Ochratoxin A biosynthesis by Aspergillus ochraceus and incidence of ochratoxigenic fungi on Wine Grapes from Southern Illinois
… with reduction in conidiation, a defect in beta-oxidation and an abnormal mitochondrial phenotype. A yeast, two-hybrid screen revealed that Aomdv1 interacts with proteins involved in regulating mitochondrial functions necessary for mycotoxin production. To further understand the role of …
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A study of the protective effects of an aspalathin enriched green rooibos extract on experimentally induced hepatic steatosis
… PPAR-α and CPT 1 involved in the regulation of beta-oxidation of lipids and reduced HMG-CoA synthase 1 (HMGCS1), the gene regulating cholesterol synthesis. Histology confirmed increased steatosis limited to zone 3 of the liver acinus synonymous with NAFLD. Treatment with GRT did not …
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Proteome studies on leaf peroxisomes from Spinacia oleracea L. and Arabidopsis thaliana (L.) Heynh.
… die in Photorespiration, Fettsäure-beta-Oxidation und den Metabolism reaktiver Sauerstoffspezies involvierten Enzyme, wurde einige neue Proteine identifiziert, und zwar eine kurzkettige Alkoholdehydrogenase, ein Naphthoat-Synthase-ähnliches Protein, eine Enoyl-CoA-Hydratase/Isomerase …
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