Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"Beta-lactamases"”.
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Role of extended spectrum beta lactamases producing E. coli and Acanthamoeba in urinary tract infections
… resistance caused by Extended-Spectrum β-lactamases (ESBLs) producing organisms, particularly E. coli, have become an increasing problem, and recurrent infections are not uncommon. It has been confirmed that pathogenic bacteria survive and multiply inside the protozoan parasite, …
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Genotipagem e pesquisa de metalo-beta-lactamases em isolados clínicos de Pseudomonas aeruginosa resistentes aos carbapenęmicos /
Orientadora: Libera Maria Dalla Costa
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The emergence of <i>Escherichia coli</i> with CTX-M extended-spectrum beta-lactamases in the United Kingdom
In the past decade, multi-resistant <i>Escherichia coli</i> with CTX-M enzymes have rapidly become the leading producers of extended-spectrum β-Iactamases (ESBLs) worldwide. <i>E. coli</i> with CTX-M-15 β-Iactamases are the most common, and are now endemic in many UK hospitals and in the community. …
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Multiple levels of regulation are associated with the production of CTX-M-14 and CTX-M-15 beta-lactamases in Escherichia coli
The prevalence of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae is increasing rapidly. CTX-M type β-lactamases are the most prominent ESBL family worldwide and are produced mainly by E. coli. blaCTX-M-14 and blaCTX-M-15 genes are the dominant alleles circulating worldwide. …
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Antimicrobial Resistance Mediated By Synthesis of Richmond and Sykes Type I Beta-Lactamase
A number of beta-lactam antibiotics that are relatively resistant to hydrolysis by beta-lactamases have been developed. These new compounds have expanded antibacterial activity but also have posed several challenging clinical problems including therapeutic failures and relapses of infections. …
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Mechanisms of Regulation and Resistance for Plasmid-Encoded ampC Beta-Lactamase Genes
BETA-lactam antibiotics are the largest class of antimicrobial drugs and the most frequently prescribed world wide. As the use of these agents increased so did the evolution of bacterial BETA-lactam resistance. BETA-lactamases are collectively the most commonly identified BETA-lactam resistance …
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Occurrence of extended –spectrum beta-lactamase-producing enterobacteriaceae and bacterial loads in dust from poultry farms in Lusaka-Zambia.
… is detrimental when inhaled. Extended Spectrum beta lactamases are a universal public health alarm which are frequently identified in humans and animals including poultry. Poultry dust is a possible source of drug resistant microorganisms including Extended spectrum beta lactamases which confer …
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Occurrence of extended –spectrum beta-lactamase-producing enterobacteriaceae and bacterial loads in dust from poultry farms in Lusaka-Zambia.
… is detrimental when inhaled. Extended Spectrum beta lactamases are a universal public health alarm which are frequently identified in humans and animals including poultry. Poultry dust is a possible source of drug resistant microorganisms including Extended spectrum beta lactamases which confer …
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Molecular methods for the detection of TEM- and SHV-related beta lactamase genes in members of the Enterobacteriaceae
… is a common and important clinical problem. Beta lactam resistance in Gram negative bacilli is mediated predominantly by beta lactamases, enzymes able to hydrolyse the beta lactam ring. The commonest plasmid mediated beta lactamases in the Enterobacteriaceae are those related to either TEM-1 …
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Molecular basis of the evolution of new protein functions: Kemp elimination and phosphoryl transfer reactions
… novo designed Kemp Eliminase (KE07), the metallo-beta-lactamases NDM1 and VIM2, and the N-acyl-homoserine lactonase AiiA. Based on these studies, I was able to identify three clear phenomena that are important in molecular evolution: first, preorganization of the active sites residues is essential …
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Molecular basis of the evolution of new protein functions: Kemp elimination and phosphoryl transfer reactions
… novo designed Kemp Eliminase (KE07), the metallo-beta-lactamases NDM1 and VIM2, and the N-acyl-homoserine lactonase AiiA. Based on these studies, I was able to identify three clear phenomena that are important in molecular evolution: first, preorganization of the active sites residues is essential …
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Impacto da resistência bacteriana no combate das infecções relacionadas à assistência à saúde.
… that produce enzymes such as extended-spectrum beta-lactamases (ESBL), AmpC and carbapenemases, especially KPC-1 and NDM, which can degrade antimicrobial and produce modifications that prevent the entry or change the action site of drugs that are part of the resistance mechanisms of Gram …
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A study on the detection of extended spectrum beta lactamase producers and class I intergrons in e. coli isolates from urinary tract infected patients at UTH.
Escherichia coli that produce extended spectrum beta lactamase (ESBL) enzymes pose a global challenge in the management of urinary tract infections (UTIs) caused by these organisms. Beta lactamases are the primary cause of resistance to beta lactam antibiotics. These enzymes confer multi drug …
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A study on the detection of extended spectrum beta lactamase producers and class I intergrons in e. coli isolates from urinary tract infected patients at UTH.
Escherichia coli that produce extended spectrum beta lactamase (ESBL) enzymes pose a global challenge in the management of urinary tract infections (UTIs) caused by these organisms. Beta lactamases are the primary cause of resistance to beta lactam antibiotics. These enzymes confer multi drug …
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Isolation and characterization of genes from beta-lactam antibiotic producing organisms
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Phenotypic and genotypic characterization of salmonella isolates from chickens and humans in South Sudan.
… tetracycline 7 (87%), erythromycin 4 (50%), β-lactamases 6 (75%), erythromycin 4 (50%), streptomycin 4 (50%) and chloramphenicol 2 (25%). The gene sul1 and sul2 (8 isolates) was the most frequently detected followed by the gene tet(D) and tet(A) (7 isolates), and blaCTX-M-15 (6 isolates). The …
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Evaluation of the Interplay between β-Lactamase Expression and Porin Loss in β-Lactam Susceptibility Profiles in Escherichia coli
… driven by the acquisition of Extended-Spectrum β-Lactamases (ESBLs) and carbapenemases. However, β-lactam resistance in E. coli is often multifactorial, arising from different mechanisms such as the combined effects of β-lactamase production, alterations in outer membrane permeability, and …
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Defining the Aetiology and Antimicrobial Susceptibility Patterns of the Predominant Bacteria Associated with Bloodstream Infections at the Hospital for Tropical Diseases in Ho Chi Minh City, Vietnam
… genes. These genes include extended spectrum Beta lactamases (ESBLs) and AmpC lactamases in the Enterobacteriaceae, methicillin-resistance genes in <i>Staphylococcus aureus</i>, carbapenemase-resistance genes in Gram-negative bacilli and vancomycin-resistance genes in enterococcus. Asian …
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Sélection et caractérisation de Nanobodies inhibiteurs de métallo-β-lactamases
… des facteurs de résistance. La production de β-lactamases par des souches infectieuses est le principal mode de résistance aux antibiotiques à noyau β-lactame. Ces enzymes hydrolysent le noyau β-lactame de ces antibiotiques, les empêchant ainsi d’exercer leur action lytique. Parmi les …