Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Beta Cell Regeneration"”.
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Tracing of Alpha-to-Beta Cell Transition Following Treatment with CHIR-Injected Human Multipotent Stromal Cell Secreted Proteins
… manages symptoms but cannot restore endogenous beta cell function. Regenerative strategies have demonstrated beta-cell neogenesis following ablation; however, the cellular mechanisms driving islet regeneration remain unclear. Previous work from the Hess Lab has shown that human bone …
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Developing a model to assess the contribution of cytokeratin 19-expressing cells during multipotent stromal cell-induced islet regeneration
… in human bone marrow-derived multipotent stromal cells (hMSC) generated conditioned media (CM) that promoted β-cell regeneration in streptozotocin-treated mice. Ductal-derived endocrine progenitors, which have been shown to generate β-cells following pancreatic injury, represent a candidate for …
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THE VASCULAR RESPONSE WITHIN THE ISLET DURING BETA CELL DEVELOPMENT AND REGENERATION
… capillary bed, to develop into the appropriate cell type. The neonatal rat pancreas undergoes a developmental β cell turnover that involves the apoptosis of immature β cells and their replacement with adult β cells. To further elucidate this mechanism and the potential role of the vascular …