Global ETD Search
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Showing 1 to 8 of 8 for “"Benzothiazoles"”.
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Quarternisation of Benzothiazoles and 1,2,3 - Benzothiadiazoles
The chemistry of 1,2,3-benzothiadiazola is briefly reviewed. The early work on the preparation and properties of methyl- and ethyl-1,2,3-benzothiadiazolium salts is described, and more recent work on 2-aryl-l,2,5-benzothiadiazolium salts is summarised. The limitations of methyl and ethyl iodides as …
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Excited state proton transfer in 2-substituted benzothiazoles
The photophysics of 2-(2'-hydroxyphenyl)benzothiazole (HBT) and related compounds has been studied as a function of solvent, pH or H 0 and temperature. Measurements of absorption and fluorescence spectra and fluorescence decay profiles under these various conditions have been combined with …
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Elucidation of the Mechanism of Action of a Cell Line Selective Toxin
… to identify two chemical series, oxalamides and benzothiazoles, that were selectively toxic to the same four of 12 lung cancer cell lines at low nanomolar concentrations. Sensitive cell lines expressed cytochrome P450 (CYP) 4F11, which metabolized the compounds into irreversible stearoyl CoA …
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Development of transition metal-catalyzed C-S and C-C cross-coupling reactions
… protocols for the synthesis of vinyl sulfides, benzothiazoles and benzoxazoles, using transition-metal-based catalysis. Furthermore, the mechanism of these cross-coupling reactions has also been investigated. Although numerous methods have been developed for the stereoselective synthesis of …
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The application of soluble supports in the radiochemical asymmetric total synthesis of tea flavanols.
… for the preparation of 2-(2'-arylethylsufonyl)benzothiazoles. Alkylcopper reagents were also suitable substrates for this novel coupling. Heck reaction between aryl iodide and phenyl vinyl sulfone, and reduction of the resulting alkene gave 2-arylethyl phenyl sulfone but the Heck reaction …
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A study of benzazole derivatives showing large stokes shifts
… fluorescence properties of 2-(2-hydroxyphenyl)benzothiazoles in solution depend critically on the solvent and on the nature of other substituents present in the 2-phenyl ring. Each of the main emission peaks in the fluorescence spectra has been attributed to particular species. Fluorescence …
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Structure guided discovery of inhibitors of indoleamine 2,3-dioxygenase (IDO1)
… included compounds from the chemical classes: benzothiazoles, benzimidazoles, benzoxazoles, indoles, indan‐1‐ones, quinolines, naphthalenes, coumarins, biphenyls, phenols, 4‐phenylimidazole, pyridines, hydroxyamidines and phenylpyruvic acids. Spectroscopic studies show that these compounds …