Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Benserazide"”.
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Structure-Activity Relationship Studies of Mitochondrial Uncouplers and PilB Inhibitors
… the structure-activity relationship of benserazide in the pursuit of treating drug-resistant bacterial diseases. Antimicrobial resistance is an imminent health threat worldwide due to the increasing resistances to common antibiotics of many lethal pathogens. Overuse and underdevelopment …
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The Type IV Pilus Assembly ATPase PilB as a Regulator of Biofilm Formation and an Antivirulence Target
… chemical library led to the identification of benserazide and levodopa as CtPilB inhibitors. We show that both compounds inhibit T4P assembly in M. xanthus without any detrimental effects on bacterial growth. Furthermore we demonstrate that both levodopa and benserazide inhibit T4P-mediated …
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Therapeutic strategies of Parkinson's disease: Alternative dopamine replacement and potential drug targets
… via oral tablet dosing of L-DOPA/carbidopa or benserazide 3-4 times/day remains the most effective and well-tolerated treatment, one that significantly improves the motor symptoms and quality of life of patients in the early stages of PD. However, due to L-DOPA's non-continuous, pulsatile …
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Anatomical and Physiological Characterization of Striatal Activation of the Cerebral Cortex
… compared with WT mice. 10mg/kg L-dopa and 3mg/kg benserazide systemic administration significantly increased the c-Fos expression in the striatum, the entire cerebral cortex including the motor cortex, and the key brain areas in striatal-thalamocortical circuit (motor thalamus, GPe, STN, and SNr) …