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Showing 1 to 2 of 2 for “"Bempedoic acid"”.
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The use of bempedoic acid in treating hypercholesterolemia
… mechanisms unlike those targeted by statins. Bempedoic acid, an oral prodrug that upon activation reduces LDL-C by inhibition of ATP citrate lyase, has been thoroughly evaluated as one such therapy for treating hypercholesterolemia. Through a variety of clinical trials, bempedoic acid, …
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MOLECULAR REGULATION OF ATP-CITRATE LYASE
… Finally, I discuss pertinent literature on bempedoic acid (BPA), a first-in-class drug for the treatment of hypercholesterolemia and cardiac risk reduction, by which inhibition of ACLY in the liver is widely accepted as the major mechanism. However, BPA treatment also has effects on lipid …