Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Beige fat"”.
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The Aging-Induced Decline in Beige Adipose Tissue Development
… Unlike energy-storing white adipose tissue, beige adipose tissue burns energy in the form of heat and thus has therapeutic potential to increase energy expenditure and combat obesity. Aging has been shown to decrease the amount and function of beige adipose tissue, but the mechanism is …
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Dissecting NAMPT Signaling Pathways in Beige Adipocyte Development, Impairment and Maintenance
… reduce the abundance and function of thermogenic beige and brown adipocytes, lowering energy expenditure and worsening metabolic disease. Beige adipocytes arise within white adipose tissue in response to environmental and hormonal cues, whereas brown adipose tissue is a dedicated thermogenic …
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The Reprogramming of White Adipose Tissue to Brown Adipose Tissue Mediates Adverse Metabolic Dysfunction After A Burn Injury
… BAT burns excess energy in the form heat. This fat burning aspect of BAT has emerged as a powerful tool in combating the metabolic syndrome (hyperglycemia, excess body fat, hypertension). Additionally, it has been discovered that our WAT can be reprogrammed to become BAT, however, whether or not …
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Metabolic regulation by nuclear receptor FXR and micro RNA-34a in health and disease
… type 2 diabetes, cardiovascular disease, fatty liver diseases and other human disease like female infertility, mental depression and even certain types of cancer. Obesity, characterized by excessive body weight, is often considered to result from an imbalance between energy intake and …
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Using immune cells to combat obesity: adipose eosinophils as mediators of metabolic homeostasis
… from white adipose tissue to energy-burning beige adipose tissue. In this thesis, we focused on adipose eosinophils as a key player in the immune regulation of metabolic homeostasis, by focusing on their roles in promoting adipose tissue angiogenesis and thermogenesis, which expends energy …