Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 24 for “"Behavioural tests"”.
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Exploring the Behavioural Effects of Compound-21 Using Novel Object Recognition and Object in Place Tests in Long Evans Rats
… behaviour in rodents. When used with spontaneous behavioural tests of memory in rodents, DREADDs allow for a unique opportunity to advance our understanding of how specific neuronal populations contribute to cognition. While data on the use of DREADDs to study memory with spontaneous tasks in rats …
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Locus-coeruleus norepinephrine system function in a developmental animal model of schizophrenia: the socially isolated rat
… attentional abnormalities in isolated rats in behavioural tests which correspond to the results of studies investigating the cognitive symptoms of schizophrenia in patient trials. Isolated rats also display abnormal social responses which may be of relevance to the negative symptoms of …
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Temperament in beef cattle : methods of measurement, consistency and relationship to production
Two behavioural studies were conducted at the University of Saskatchewan beef feedlot. In the first study, the temperament of 400 steers was determined using both objective and subjective measures. The consistency of temperament, over repeated tests and between different measures, was also tested. …
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Literal and figurative meanings of Spanish spatial prepositions in Chinese students’ acquisition of Spanish as a third language
… of this group of participants in four behavioural tests is compared. The tests were a lexical identification task, a picture fill-in-the- blank task, a sentence generation task and a truth value judgment task. These tests were conducted both in Spanish, which the participants had begun …
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Event-Related Potential Brain Correlates of Episodic and Semantic Memory in Adults with Autism Spectrum Disorder
… This thesis built upon recently established behavioural patterns of preserved semantic and diminished episodic memory in ASD, by linking these with established patterns of electrophysiological activity in different cortical regions of the brain in TD individuals. Event-Related Potential (ERP) …
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Exploring Dystrophin-Mediated Control of Neural Stem Cell Fate Associated with Intellectual Disability In Duchenne Muscular Dystrophy Patients
… the muscle phenotype is well-established, behavioural characterization of the mdx mouse model has been inconclusive. In this thesis I investigated the hippocampal and amygdala cellular and behavioural phenotypes of the mdx mouse. I show that post-natal neural stem-like cell division in the …
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From Animals to Algorithms: Comparative Psychology for the Study of Artificial Intelligence
… While many have advocated for conducting behavioural experiments on AI systems, treating them as though they are participants in the laboratory, the value of a comparative psychological approach has been underappreciated (Chapter 1). In Chapter 2, I critique the common practice of …
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Ethanol exposure during synaptogenesis in a mouse model of fetal alcohol spectrum disorders: acute and long-term effects on gene expression and behaviour
… resulting in a broad range of physiological, behavioural, and cognitive phenotypes that characterize ‘fetal alcohol spectrum disorders’ (FASD). Factors affecting the manifestation of these phenotypes include alcohol dosage, timing of exposure, and pattern of maternal alcohol consumption; …
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Activity and Structure of Auditory Brain Neurons Underlying Phonotactic Behaviour in Female Crickets
… sound patterns with varied pulse period. Recent behavioural tests were performed by systematically varying single pulse durations or inter-pulse intervals, which also led to the design of a chirp pattern with 5-20-50 ms pulses that is attractive when played forward, but non-attractive when the …
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The circuit basis of olfactory mate recognition and localisation
… We used connectomics, functional imaging, and behavioural tests to investigate the anatomy and function of a circuitry dedicated to processing cis-vaccenyl acetate (cVA) a male pheromone signal. We discovered a previously unknown second order projection neuron class (PN) that senses cVA, and …
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Brain-behavioural olfactory asymmetries in Apoidea
… organisms. Over groups of individuals, brain-behavioural asymmetries might present a direction in the occurrence of the bias (the majority of the individuals showing the same direction at the population level) that has been mathematically demonstrated to be an evolutionarily stable strategy in …
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Investigating the role of eEF1A2 in motor neuron degeneration
… motor neuron degeneration. A combination of behavioural tests and pathology was used to compare wild type and heterozygous mice up to 21 months of age. Whilst results indicate that there is no significant difference between ageing heterozygotes and wildtype controls, there is an indication …
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Discerning nonlinear brain dynamics from EEG : an application to autistic spectrum disorder in young children
… the case that the diagnosis of ASD is based on behavioural tests and interviews. This thesis describes a step-by-step characterisation and comparison of brain dynamics from ASD and neurotypical subjects, based on the analysis of multi-probe EEG time-series from male children aged 3-5 years. The …
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Touching Autism Spectrum Disorder: Somatosensory Abnormalities in Shank3b and Cntnap2 Mouse Models
… behaviour. The diagnosis of autism is based on behavioural observation of the subject as research has not yet identified specific markers. Today, several studies show that disturbances in sensory processing are a crucial feature of autism. Indeed, around 90% of individuals diagnosed with autism …
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Mechanism of transcranial focused ultrasound regulating the neuronal activity of the retrosplenial cortex
… how tFUS regulates neuronal activity, I used behavioural tests, real-time fluorescence quantitative polymerase chain reaction, immunofluorescent staining, chemical genetics, and multi-channel in vivo recording to explore whether tFUS affected neuronal activity in the pain-related brain region, …
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The role of ventromedial and dorsolateral prefrontal cortex in physiological and behavioural dysfunction in non-human primates, of relevance to mood and anxiety disorders
… and inactivation of area 25 in two behavioural tests assessing motivational and consummatory behaviour of relevance to the symptom of anhedonia, the loss of pleasure. In chapter four the effect of the local increase of cortisol in area 25 in three domains of motivational, …
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Importance of floral scent compounds for the interaction between Silene latifolia (Caryophyllaceae) and the nursery pollinator Hadena bicruris (Lepidoptera: Noctuidae)
… latifolia. Furthermore, electrophysiological and behavioural tests with floral scent extracts and single authentic standard compounds were carried out in H. bicruris to identify the attractive compounds of the complex floral scent. To get an insight into the role of floral scent in guiding …
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Exploration of cognitive and neurochemical deficits in an animal model of schizophrenia. Investigation into sub-chronic PCP-induced cognitive deficits using behavioural, neurochemical and electrophysiological techniques; and use of receptor-selective agents to study the pharmacology of antipsychotics in female rats.
… in rats to investigate cognitive dysfunction in behavioural tests which have been highlighted as relevance by the MATRICS initiative (MATRICS.ucla.edu). The main tests used were attentional set-shifting, operant reversal learning, and novel object recognition tasks. The pharmacology of …
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Validation of an animal model of cognitive dysfunction associated with schizophrenia. Development and validation of the novel object recognition task using behavioural manipulations and psychotomimetic dosing regimens to induce cognitive deficits of relevance to schizophrenia in hooded-Lister rats.
… treatment with PCP induces cognitive deficits in behavioural tests of relevance to cognition associated with schizophrenia. This may allow the detection of novel pharmacotherapies to alleviate these cognitive deficits and exploration of the nature of cognitive disturbances in these patients.
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Bio-behavioural evaluation of efavirenz and Δ9-tetrahydrocannabinol alone and in combination in rats with respect to psychosis and anxiety
… of EFV. One study noted that the pre-dominate behavioural profile of EFV is similar to that of the hallucinogen, lysergic acid diethylamide (LSD), with EFV having weak partial agonist activity at the serotonin 5-HT2A receptor subtype, while another study reported that EFV induces depression and …
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