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Showing 1 to 2 of 2 for “"Behavioural Pharmacology"”.
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Characterisation of the role of peripheral μ-opioid receptors in the behavioural effects of heroin and their underlying neural systems in the rat
The behavioural effects of opioids such as heroin have long been considered to be mediated by central mechanisms. However in recreational use, opioids are administered systemically and can therefore influence peripheral μ-opioid receptor-dependent systems before they reach the brain. In humans, …
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Ultra-Low Dose Antagonist Effects on Cannabinoids and Opioids in Models of Pain: Is Less More?
An ultra-low dose of a drug is approximately 1000-fold lower than the dose range traditionally used to induce a therapeutic effect. The purpose of the present thesis was to broaden the knowledge of the ultra-low dose effect, that was previously identified in the opioid receptor system, by looking …