Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"Bed rest"”.
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Effects of Leucine on Skeletal Muscle During 14 d Bed Rest in Middle-aged Adults
… a largely unstudied age group, during 14 d bed rest (BR) and subsequent 7 d rehabilitation. Primary findings were: 1) leucine attenuated the loss of whole body lean mass during the first 7 d of BR compared to control subjects (LEU: -0.6±0.2 kg vs. CON: -1.1±0.2 kg, p<0.05) and reduced or …
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A convergent parallel mixed method study on the experience of coping during high-risk pregnancy and prescribed bed rest
Antepartum bed rest and hospitalization are frequently prescribed for high-risk women experiencing pregnancy complications. Bed rest may result in problems for the high-risk mother including isolation, boredom, anxiety, depression and separation from their families. The aim of this study is to …
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Physiological, Psychosocial, Behavioral, Socio-demographic Risk Factors and Antepartum Bed Rest Associated with Gestational Age at Birth and Postpartum Depression in High Risk Pregnant Women
… depression; 2) assess whether antepartum bed rest moderates the relationship between risk factors and gestational age at birth and postpartum depression; and 3) compare gestational age at birth, birth weight, length of NICU stay and postpartum depression of high risk women with bed rest to …
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Principal component based system identification and its application to the study of cardiovascular regulation
… (OI). Experimental data from a prolonged bed rest study (simulation of microgravity condition) are analyzed and the conclusions are: 1) prolonged bed rest may impair autonomic control of heart rate; 2) orthostatic intolerance after bed rest is associated with impaired sympathetic …
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Early mobilisation after coronary angiography to reduce back pain
… After the procedure, the patient remains on bed rest (mainly supine with the affected leg straight) for at least a further 4-6 hours (Sabo, Chlan and Savik, 2008) in order to reduce the chances of complications at the groin site (Chair, Taylor-Piliae, Lam and Chan, 2003). Due to this enforced …
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Computational and biological studies of mechanical prophylaxis against deep venous thrombosis
… resulting from prolonged periods of bed-rest or immobilization of the limbs. One of the most effective methods of prophylaxis against DVT is external pneumatic compression (EPC). In spite of its wide acceptance as an effective means of prophylaxis, its mechanism remains poorly …
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The role of osteocytes in disuse and microgravity-induces bone loss
… and that reduced loading, as in prolonged bed rest or space flight, leads to bone loss. Osteocytes, the most abundant bone cell type, are thought to be key mechanical sensors in bone, yet the molecular mechanism of this action remains poorly understood. Improved understanding of how …
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Comparative Plasma Proteomics in Muscle Atrophy Induced by Cancer Cachexia and Hindlimb Unloading
… multiple pathologies such as cancer and extended bed rest. Atrophy reduces overall quality of life while increasing morbidity and mortality. Currently, efficacious therapeutic interventions to treat and prevent muscle wasting in all its forms are lacking, however if conserved mechanisms can be …
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Skeletal adaptation to reduced mechanical loading
… cord injury, stroke, muscular dystrophy, and bed rest. The overall goal of this work was to study skeletal adaptation to varying amounts of reduced loading to help delineate the relationship between mechanical stimuli and skeletal adaptation. We first examined the relative contribution of …
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Skeletal adaptation to reduced mechanical loading
… cord injury, stroke, muscular dystrophy, and bed rest. The overall goal of this work was to study skeletal adaptation to varying amounts of reduced loading to help delineate the relationship between mechanical stimuli and skeletal adaptation. We first examined the relative contribution of …
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Soft pneumatic devices for blood circulation improvement
… meant to apply an intermittent massage and to restore blood circulation in lower limbs in order to improve cardiac output and wellness in general. The choice of the actuators, as well as the pneumatic circuits and air distribution system and PLC control patterns will be outlined. The trial run …
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Development of a stem cell-based therapy for the recovery of skeletal muscle mass following immobilization
… as result of limb immobilization and whole body bed rest. Severe reductions to muscle mass contribute to functional declines, disability, and metabolic comorbidities, such as obesity, Type II diabetes, and cardiovascular disease. Physical rehabilitation is the most commonly prescribed therapy to …
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Development of a pericyte-based strategy to recover aged skeletal muscle after disuse
… mass that occurs after periods of extended bed rest or immobilization. Recovery via physical rehabilitation is often incomplete in special populations such as older adults, due to injury and pain, functional limitations, and anabolic resistance. Prolonged loss of muscle can lead to metabolic …
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Optimization of a pericyte therapy to improve muscle recovery following hindlimb immobilization
Extended bed rest or single limb immobilization can significantly reduce skeletal muscle mass and function. Recovery may be severely delayed or incomplete due to the inability to effectively engage in physical therapy. Thus, alternative strategies are needed to enhance recovery and prevent …
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Development of a pericyte-derived extracellular vesicle therapy for the recovery of skeletal muscle mass following immobilization
Extended bed rest and single limb immobilization (casting) are necessary for tissue healing during periods of illness, disease and/or injury. Unfortunately, prolonged inactivity can result in significant declines in protein synthesis and skeletal muscle mass, a condition known as disuse atrophy. …