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Showing 1 to 1 of 1 for “"Bayesian HMM"”.
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Bayesian Hidden Markov Models for finding DNA Copy Number Changes from SNP Genotyping Arrays
… of genetics research. This dissertation develops Bayesian HMMs for finding CNVs from single nucleotide polymorphism (SNP) arrays. A Bayesian framework to reconstruct the DNA copy number sequence from the observed sequence of SNP array measurements is proposed. A Markov chain Monte Carlo (MCMC) …