Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Batf"”.
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Batf regulates previously unknown AP-1 target genes to control TH17 differentiation
… of AP-1 activity. We found that the AP-1 protein Batf, which lacks a TAD, is highly expressed in T helper cells compared to various other immune cells and tissues. IL-17-producing T helper: TH17) cells are a CD4+ T cell subset that coordinates inflammatory responses in host defense but are …
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Relación entre NETs, microbiota intestinal y translocación bacteriana en pacientes infectados por VIH y en un modelo animal con depleción de BATF
… y la barrera intestinal. El modelo de ratones Batf-/- (knock-out), que presenta un déficit de linfocitos Th17 similar al observado en PLWH con carga viral controlada, permite estudiar estos fenómenos en condiciones controladas. OBJETIVOS En PLWH con carga viral indetectable, se plantea como …
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Internet and U.S. citizen militias
… Bureau of Alcohol, Firearms and Tobacco (BATF) raids at Ruby Ridge, Idaho and Waco, Texas were mentioned most often as movement precipitants. Based on the militiamen studied, the militia movement was Internet-driven, although a number of alternative media played a joint role in movement …
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Transcription factors and cis-acting elements in T helper cell cytokine expression
… promote Th9 development include STATs, PU.1, BATF, and IRF4. In this study, we identify ETV5 as a factor that promotes IL-9 and IL-10 production by binding to cis-acting regulatory elements in the respective genes. At the Il9 gene, ETV5 cooperates with PU.1 in regulating gene expression. At …
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The role of BATF2 during of experimental murine Schistosomiasis
… leucine zipper transcription factor ATF-like 2 (BATF2) which belongs to a family of transcription factors critical in the control of inflammatory responses has gained enormous momentum recently as a potential target to immune deregulation during cancer and infectious diseases. We reasoned that an …
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CHARACTERIZATION OF THE EPIGENOMIC PROFILE SHAPING HUMAN FOXP3+ REGULATORY T CELL IDENTITY IN THE TUMOR MICROENVIRONMENT
… both shared and specific TF families. We confirm BATF as a crucial regulator of the activation program, shared between TI- and NAT-Tregs. Additionally, we uncover potentially relevant TFs for TI- Treg specific adaptation, with factors from non-canonical NFkB pathway among the top drivers. Overall, …
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TREM-2 and Dendritic Cells in the Pathogenesis of Allergic Airway Inflammation
… transcription factors (Zbtb46, IRF-4, IRF-8 and BATF-3) as well as high expression of costimulatory molecule CD86 and chemokine receptor CCR-7.|Whole lungs from OVA-sensitized and challenged mice were then examined for TREM-2 expression. As seen with other inflammatory conditions, TREM-2 was …