Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 149 for “"Basolateral"”.
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Dopaminergic modulation of basolateral amygdala for fear extinction
… extinction learning, a new memory is formed in basolateral amygdala (BLA) reward neurons, which inhibits the BLA fear memory. However, the neurological nature of the teaching signal that instructs the formation of fear extinction memory in BLA reward neurons is unknown. Recently work has …
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Basolateral Aamygdala circuits for differentiating positive and negative associations
… response is critical for survival. The Basolateral Amygdala (BLA) is an almond shaped structure in the brain where rewarding and fearful associations are encoded by different populations of neurons. However, identifying features of these populations have remained an enigma. My thesis …
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Influence of Sex, Adolescence, and Aging on the Rat Basolateral Amygdala
… of sex, adolescence, and aging on the rat basolateral amygdala. Study one was a neuroanatomical Golgi study that examined dendritic material in adult and aged male and female basolateral nucleus, and found significant age-related increases in dendritic material in both sexes, along with a …
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Effect of basolateral amygdaloid lesions on prolaction secretion in Peromyscus maniculatus bairdii
Call number: LD2668 .T4 1968 N67
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The molecular substrates of second-order conditioned fear in the basolateral amygdala
… of fear. Both require neuronal activity in the basolateral amygdala complex (BLA), including activation of NMDA receptors, for their encoding, and both require CaMK signalling, gene expression and DNA methylation for their consolidation. However, de novo protein synthesis is required for …
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NMDAR-PSD95-nNOS Axis-Mediated Molecular Mechanisms in the Basolateral Amygdala Underlying Fear Consolidation
… and impairs long-term potentiation of basolateral amygdala (BLA) neurons in a rodent model of auditory fear conditioning. However, the molecular mechanisms by which disrupting the PSD95-nNOS interaction attenuates fear consolidation are not well understood. Here, we used pharmacological …
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Spatial, temporal, and circuit-specific activation patterns of basolateral amygdala projection neurons during stress
… and circuit-specific activation patterns of basolateral amygdala (BLA) projection neurons during exposure to acute stress. Additionally, we explicitly tested the role of the BLA in activation of the HPA axis, as this remains a poorly understood process. Chapter 1 describes how the BLA is …
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Preparation of brush border and basolateral membrane vesicles from bovine intestine for nutrient uptake studies
Brush border and basolateral membrane vesicles were isolated by subjecting homogenized mucosal cells from bovine small intestine to a divalent cation aggregation followed by a series of differential and density gradient centrifugations. Membrane marker enzyme assays were used to monitor the …
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Examining the Roles of GABAA Receptor Subtypes in Anxiety and Anxiolysis: Focusing on the Basolateral Amygdala
… anxiolysis both systemically and within the basolateral amygdala (BLA), a brain region crucial for anxiety-like behaviors, we examined the anxiolytic-like effects, as measured by elevated-plus maze test (EPM), of several subtype selective and non-selective GABA<sub>A</sub>R positive …
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Ethanol Enhancement of Two Distinct Inhibitory Pathways in the Rat Basolateral Amygdala: Implications for Anxiety and Alcoholism
The basolateral amygdala (BLA) acts as a key interface between the interpretation of external stimuli and the production of emotional responses, such as fear and anxiety. As such, the BLA is activated in response to stressful stimuli, then integrates and projects this information to target brain …
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Development of the adolescent prefrontal cortex and basolateral amygdala and the effects of puberty and alcohol exposure
… neuroanatomical changes in the mPFC and the basolateral amygdala (BLA),dendritic arborizationsand dendritic spines were analyzed in chapter 3. These studies indicated a growth of dendrites and dendritic spines between P20 and P35 (prepuberty) in both sexes as well as both structures. After …
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ADENOSINE SYSTEM DYNAMICS AND SK CHANNELS MODULATE BASOLATERAL AMYGDALA PYRAMIDAL CELL EXCITABILITY: IMPLICATIONS FOR ANXIETY DISORDERS AND COMORBID ETHANOL ABUSE
Alcohol use disorders (AUDs) impart serious social and economic costs on society. For example, nearly 1 in 18 Americans abuses or is addicted to alcohol, contributing nearly $234 billion per year in socioeconomic costs. Despite this, effective pharmacological treatments remain elusive. To aid in …
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Mechanism of Inhibition of Transepithelial Sodium Transport in Frog Skin by Quinine and Quinidine (Noise Analysis, Cgs 4270, Basolateral Membrane)
… effects of these drugs occurred at the basolateral membranes of the cells. The drugs caused large rapid (a few minutes) increases of basolateral membrane resistance, R(,i), with little or relatively small increases of its emf, E(,i). Thereafter, while R(,i) remained above control values, …
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Influence of Carbon Dioxide on Electrophysiology and Ionic Permeability of the Basolateral Membrane of Frog Skin (Epithelia, Ionic Flux, Cellular Ph)
… accompanied by a marked depolarization of the basolateral membrane voltage as measured with intracellular microelectrodes. To study further the mechanisms involved, basolateral membrane influxes and effluxes of ('24)Na, ('42)K, and ('36)Cl were measured in control and CO(,2)-treated isolated …
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A mathematical model of the airway epithelium: Computational studies of ion and water balance
… of sodium, potassium, chloride; apical, basolateral, and transepithelial membrane potentials; cell and apical volumes. Membrane transport processes included apical passive diffusion of sodium and chloride, basolateral passive diffusion of potassium, basolateral sodium-potassium active …
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Infusion of oxytocin into the basolateral amygdala facilitates, whereas infusion into the central nucleus impairs extinction of context conditioned fear responses in rats
… OT may target other amygdala areas such as the basolateral amygdala (BLA), thereby increasing freezing responses. This thesis investigated CeA and BLA infusions of OT on the acquisition and extinction of context conditioned fear responses. In two experiments investigating the effects of OT on …
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An electrophysiological study of ion transport across the isolated perfused malpighian tubule of Onymacris plana
… of the transport mechanisms of fluid across the basolateral and apical membranes. Until now no one has investigated the isolated perfused Malpighian tubule of Onymacris plana and simultaneously measured basolateral potentials. Malpighian tubule segments (about lmm length) were dissected out and …
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A STUDY ON THE EFFECTS OF CHRONIC ALCOHOL AND WITHDRAWAL IN THE BASOLATERAL AMYGDALA OF SPRAGUE DAWLEY RATS: AFFERENT SPECIFIC MODIFICATION OF GLUTAMATERGIC NEUROTRANSMISSION
The lateral and basolateral amygdala (BLA) are major amygdala subdivisions that process environmental stimuli in an associative process that ultimately results in anxiety-like or fearful behavioral responses. These nuclei receive glutamatergic input via two major pathways differentiated by their …
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