Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Basigin (BSG)"”.
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BASIGIN-2 MEDIATED ACTIVATION OF ERK1/2 SIGNALING IN HUMAN GLIOBLASTOMA MULTIFORME CELLS
… cancer. GBM tumor cells overexpress the protein Basigin (Bsg) at the cell surface where it contributes to malignancy via stimulation of matrix metalloproteinase (MMP) expression in surrounding normal tissues, resulting in the degradation of the extracellular matrix (ECM) surrounding tumors, …
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Expression and secretion of basigin by human placental trophoblast cells occurs via microvesicle shedding and is a regulated process
… tension. Previous studies have demonstrated that basigin (BSG)/extracellular matrix metalloproteinase inducer (EMMPRIN) is able to regulate MMP production and is critical for successful implantation, angiogenesis and parturition. However, expression and specific functions of BSG during the first …
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Expression and function of basigin during early pregnancy and spermatogenesis
Basigin (BSG) is a multifunctional glycoprotein that plays an important role in both female and male reproduction since female knockout (KO) mice are infertile and male KO mice are sterile. The aim of the present study was to determine 1) whether BSG is required for proliferation of the uterine …
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Loss of basigin expression in the uterus reduces fertility in female mice
Basigin (BSG), a member of the immunoglobulin superfamily, is a transmembrane glycoprotein expressed in many cell types. It is involved in neurological processes, lymphocyte migration, angiogenesis, tissue remodeling and lactate transport. Our data show that Bsg is expressed in the reproductive …
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The Overexpression of Basigin-3 in Glioblastoma
… to target and eradicate the disease. The protein Basigin-2 (aka EMMPRIN) induces the expression of matrix metalloproteinase (MMP) enzymes, and its expression level is positively correlated with GBM tumor grade. In 2011, Liao et al. reported that a splice variant of the basigin gene, called …