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Showing 1 to 2 of 2 for “"Basic Helix-Loop-Helix Transcription Factors, Neurons, Spinal Cord"”.
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Prdm13, a Direct Downstream Target of Ptf1a, Regulates the Balance of Gabaergic Neurons versus Glutamatergic Neurons in the Dorsal Spinal Cord
… of inhibitory versus excitatory (E/I balance) neurons. The combination of basic helix-loop-helix (bHLH) and homeodomain (HD) transcription factors is essential to generate the E/I balance required for correct functioning of neural networks. During dorsal spinal cord development, the bHLH factor …
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Modulation of Excitatory and Inhibitory Neuronal Balance Through Regulation of Ptf1a by Factors Binding to Zinc Finger and POU Motifs
… balance between excitatory and inhibitory neurons. Transcription factors of the basic helix-loop-helix (bHLH) family have been shown to be particularly important in generating the correct numbers of these neurons during development. One of these, Ptf1a, is required in the specification of …