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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"Basal cell carcinoma"”.
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Detecting basal cell carcinoma in skin histopathological images using deep learning
… image classification to detect the presence of Basal Cell Carcinoma (BCC) in digital skin histological images. Since digital histology images are extremely large, we first focused on determining the presence of BCC at the patch level, using pre-trained deep convolutional neural networks as …
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THRESHOLDING METHODS FOR LESION SEGMENTATION OF BASAL CELL CARCINOMA IN DERMOSCOPY IMAGES
… that perform poorly on dermoscopy images of basal cell carcinoma (BCC), which is the most common skin cancer. One of the reasons for poor lesion detection performance is that there are very few algorithms that detect BCC borders, because they are difficult to segment, even for dermatologists. …
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Molecular Classification of Basal Cell Carcinoma of Skin by Gene Expression Profiling
Non-melanoma skin cancers (NMSC) including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are more common kinds of skin cancer. Although these tumors share common pathological and clinical features, their similarity and heterogeneity at molecular levels are not fully elaborated yet. …
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Desensitization Of Basal Cell Carcinoma To The Anti-Tumoral Effect Of Vitamin D
… BCC are few, and mostly are animal models or cell cultures. The main goal for this study is to interpret the impact of vitamin D status on the onset and progression and possibly treatment of basal cell carcinoma. Three tissue samples were collected from BCC patients (Cancer, Proximal, and …
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Evaluation of tumour-associated antigens to optically label cutaneous basal cell carcinoma for surgical excision
Basal cell carcinoma (BCC) is the most common skin cancer worldwide, with South Africa having the highest incidence rate only after Australia. The most effective treatment modality for BCC is tumor excision via Mohs surgery (pioneered by Dr. Frederic Mohs of the University of Wisconsin in 1930), a …
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Incidence of cancer among residents of high temperature geothermal areas in Iceland: A census based study 1981 to 2010
… lymphoma 3.25 (95% CI 1.73 to 6.07). The HR for basal cell carcinoma of the skin was 1.61 (95% CI 1.10 to 2.35). The HRs were increased for cancers of the nasal cavities, larynx, prostate, thyroid gland and for soft tissue sarcoma; however the 95% CI included unity. Conclusion: More precise …
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Initial implementation of epidermal electronic systems into a clinical setting to monitor cutaneous wound healing
… optimize data acquisition after the removal of basal cell carcinoma. Initial results are promising and more patients will be included to determine the feasibility, reliability, and multifunctional potential of epidermal electronic devices for wound management and other non-invasive applications.
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Basil cell carcinoma: an immunohistochemical assessment of P53, BCL-2 and CD138 in low and high-risk histological subtypes
Basal cell carcinoma (BCC) is the leading cancer in males and the second commonest cancer in females in South Africa. The cost to the health sector is expected to rise given the increasing global incidence rates, particularly of aggressive BCCs. Improved understanding of BCC is paramount to enhance …
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Aspects of skin cancer diagnosis in clinical practice
… The three most common skin cancers are basal cell carcinoma (BCC), squamous cell carcinoma (SCC) and malignant melanoma (MM). A correct diagnosis is crucial for an efficient and tailored treatment for the skin cancer patient. The purpose of this thesis was to evaluate different aspects …
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Apoptosis and Necroptosis in Basal Cell and Spinocellular Carcinoma of the Skin // Апоптоза и некроптоза при базоцелуларен и спиноцелуларен карцином на кожа
Skin carcinomas originating in the epidermis are of two main histological types: basal cell carcinoma (BCC) and spinocellular or squamous cell carcinoma (SCC). Since 2000, Bulgaria has seen a steady increase in the incidence and mortality of these neoplasms. Apoptosis is a process of programmed …
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Pioneer Factors Compete for Epigenetic Factors in Switching Stem Cell Fates
<p>During development, progenitor cells can activate one cell fate while simultaneously silencing another, a process that is tightly regulated in adult tissues. However, this process is often derailed in diseases such as cancers, leading to uncontrolled growth and malignancy. At the crossroads of …
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Chemically Based Interrogation of Smoothened, a Proto-Oncogenic Component of the Hedgehog Signal Transduction Pathway
… target in Hh-associated cancers including basal cell carcinoma (BCC) and medulloblastoma. While a Smo antagonist is now approved for the management of BCC, therapeutic strategies focused on Smo continue to encounter issues of intrinsic and acquired drug resistance. To overcome these …
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Invasion and Proliferation in Malignant Cells
Two key events in the oncogenic process of tumor cells are to acquire uncontrolled proliferation and invasive properties. This allows the tumor to grow and invade beyond the tissue from which the tumor cells originate. We here specifically studied p16 and ERK1/2 with special focus on and the …
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Primary cutaneous malignancies in the Northern Cape Province of South Africa: A retrospective histopathological review
… were identified. Most common were Squamous Cell Carcinoma (SCC), Basal Cell Carcinoma (BCC), Kaposi Sarcoma (KS), Cutaneous Malignant Melanoma (CMM) and Basosquamous carcinoma. The odds of a White male developing SCC increased by 8% each year (OR: 1.08; CI: 1.01-1.15; p-value: 0.022) whilst …
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A cancer-targeting liposomal delivery system for photodynamic diagnosis and therapy of cancers in peritoneal cavity
… is not named after the originating of cancer cells but instead contains all tumors appearing in the region of the peritoneal cavity. There are over 250,000 new cases of malignant diseases originating from organs in the peritoneal cavity annually in the USA, and most of these cases spread by …
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Cell cycle perspectives on breast cancer cell behaviour
… important characteristics of aggressive tumour cells. Previous observations in both colorectal cancer and basal cell carcinoma indicated that infiltrative tumour cell behaviour might be counteracted by a high proliferative activity, suggesting a coordination of these two activities at the …
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Novel Cutaneous Human Papillomaviruses and Biomarkers in the Skin Lesions
… skin cancer (NMSC), comprising of squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), is the most prevalent cancer amongst Caucasians. The main risk factor for the development of NMSC is UV-irradiation but human papillo-mavirus (HPV) might be a co-factor. We extended the …
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The transcription factor Zfx is required for tumorigenesis caused by Hedgehog pathway activation
… pathway regulates normal development and cell proliferation across the metazoa. Upon its aberrant activation, mammalian Hh signaling can also cause tumor formation. Hh-induced tumors can arise from different tissues and can be locally invasive but rarely metastatic or highly aggressive, as …
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Periocular malignancy.
… involve the eyelids in order of frequency are: basal cell carcinoma (90%), squamous cell carcinoma (5-8%), sebaceous gland carcinoma (2-3%) and melanoma (1%). The eyelids represent a high risk area for recurrence and are also functionally integral to the protection of the eye. Hence, surgical …
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Diversity of Skin Infections
… link to infection. NMSC, including squamous cell carcinoma (SCC) and basal cell carcinoma, is the most common cancer among Caucasians. Ultraviolet radiation is an established risk factor. Human papillomaviruses (HPVs) have been established as the major cause of cervical cancer. Many NMSCs …
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