Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"Barbituric acid"”.
-
Preparation of Pyridinium and Diaminocarbonium Barbituric Acid Ylides
Through NMR experiments of the reaction of barbituric acid with carbodiimide, a general synthetic procedure for the preparation of 5-diaminomethylenebarbiturates (DABA) was developed. This procedure is very simple and applicable to the preparation of large quantities of DABA derivatives. Through …
-
Some Antibacterial Effects of Barbituric Acid and Related Derivatives
Made available in DSpace on 2014-12-05T17:47:52Z (GMT). No. of bitstreams: 1 6402862.pdf: 2924268 bytes, checksum: 1689909b00372b176c515ea61ba856b6 (MD5) Previous issue date: 1963
-
The Design and Synthesis of Novel Barbiturates of Pharmaceutical Interest
Barbituric acids have been historically classified as compounds that act on the central nervous system, and as such provide therapeutic uses as anxiolytics, sedatives, hypnotics, and anticonvulsants. Recent investigations of barbituric acid derivatives have provided scientists with information that …
-
The crystal and molecular structures of some transition metal-barbiturate complexes
… metal, barb is the anion of a substituted barbituric acid and L is an organic base. These compounds are of importance in the clinical detection and identification of barbiturate drugs and this aspect is discussed in a later section. An infrared study of these compounds is also described. …
-
ISPH fusion proteins, ISPH inhibition, and bisphosphonate mechanism of action
… testing of the top hits identified a spirocyclic barbituric acid that exhibited a Ki of ~ 500 nM against Pseudomonas aeruginosa IspH. Synthesis of related molecules identified a benzyl containing analog with a Ki of ~ 3 μM against E. coli IspH. This was the first report of a non-diphosphate …