Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"Bacterial translocation"”.
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Η ΕΠΙΔΡΑΣΗ ΤΗΣ ΑΣΙΤΙΑΣ, ΠΡΩΤΕΙΝΙΚΗΣ ΔΥΣΘΡΕΨΙΑΣ, ΚΥΤΤΑΡΟΣΤΑΤΙΚΩΝ ΚΑΙ ΑΝΤΙΒΙΟΤΙΚΩΝ, ΣΤΗΝ ΑΚΕΡΑΙΟΤΗΤΑ ΤΟΥ ΒΛΕΝΝΟΓΟΝΙΟΥ ΕΝΤΕΡΙΚΟΥ ΦΡΑΓΜΟΥ. (ΠΕΙΡΑΜΑΤΙΚΗ ΜΕΛΕΤΗ)
… EITHER ALONE OR INCOMBINATION. WE STUDIED THE BACTERIAL TRANSLOCATION FROM THE INTESTINAL LUMEN TO MESENTERIC LYMPH NODES, LIVER, SPLEEN, KIDNEY AND LUNGS, BY CULTURING TISSUES FROM THE ABOVE ORGANS AFTER SACRIFICE. THE PERIOD OF STUDY WAS 24-72 H, AFTERTREATMENT. THE TERMINAL ILEUM OF EACH …
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Composición de la microbiota en pacientes pediátricos con déficit de hormona de crecimiento antes y después de recibir tratamiento con hormona de crecimiento
… data, analytical data, markers of inflammation, bacterial translocation and also the composition of the microbiome was determined by massive sequencing of the 16S rRNA gene, with comparison between cases and controls. The same data were analysed in patients with GH deficiency after treatment with …
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Effects of different antiretroviral treatments on gut microbiota of hiv-infected patients
… in gut microbiota (dysbiosis). Increased bacterial translocation and alterations to gut microbiota composition have been observed in HIV-infected patients and contribute to immune activation and inflammation. This Doctoral Thesis demonstrates, in clinical practice, that not only HIV …
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Transport of copiotrophic bacteria in oligotrophic coarse soils: a Monte Carlo analysis
… thought to be oligotrophic. A stochastic bacterial transport model was developed to analyze bacterial translocation in coarse-grained, mountainous soils beneath a hypothetical drainfield/soil interface. Specific model parameters were randomly generated using a procedure known to produce …
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A genomic investigation into gastrointestinal antimicrobial resistance and clinical infection in patients undergoing transplantation
… BSI-associated AMR; 2) study the phenomenon of bacterial translocation in two distinct cohorts of transplant recipients – Small Bowel Transplantation and Haematopoietic Stem Cell Transplantation; and 3) illustrate the longitudinal evolution of AMR in these transplant cohorts. Using genomic data, …
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Host parasite interaction in a mouse model of inflammatory bowel disease
… epithelial barrier dysfunction play a role in translocationof bacteria and the development of colitis? Our results reveal that mdrla KO mice have amore Th 1 type of gut environment and delayed worm expulsion compared to the wild type. Inaddition, we found that mice susceptible to colitis …
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Determining the impact of Heligmosomoides polygyrus infection on the development of colitis
… DSS colitis is characterised by significant bacterial translocation to the spleen, which is concluded to be due to loss of intestinal epithelial integrity. Helminth infection also resulted in a microbial shift of translocating bacteria following DSS administration, as evidenced by gram …
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Moderate Acute Malnutrition: Inflammatory Response, Microbiota, and Potential Treatments
… exhibited intestinal dysbiosis and increased bacterial translocation. Use of the antibiotic vancomycin further exacerbated intestinal dysbiosis in MN mice by increasing the proportion of Gammaproteobacteria; these mice also had increased inflammatory cytokine response to LPS challenge. …
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Pathogenic Mechanisms Underlying Immune Dysregulation Associated To Hypomorphic RAG2 Mutation: Role Of Microbiota At Mucosal Interfaces
… the composition of the gut microbiota and causes bacterial translocation across the intestinal epithelium. Furthermore, loss of T cell tolerance to the commensal microbiota leads to gut inflammation sustained by Th1 and Th17 cells. Interestingly, we provided evidence that these gut-derived …
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Intestinal Inflammation Model Inducing Gut Leakage by Different Methods in Broiler Chickens Using FITC-d as a Marker
… of aerobic bacteria in liver as an index of bacterial translocation (BT), differential white blood cell counts, and immune organs in broiler chickens. DEX-treated chickens showed a significant increase in serum FITC-d and BT, again indicating that stress increased paracellular leakage across …
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Effects of Acute Alcohol Exposure on Post Burn Intestinal Immunity: Role of IL-23
… intestinal tissue damage, leakiness and bacterial translocation as well as intestinal T lymphocyte suppression following EtOH intoxication and burn injury.</p> <p>Th17 cells are implicated in gut homeostasis and in the containment of gut pathogens. We investigated the effects of EtOH …
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Follow your gut: Does AKR1D1 impact gastrointestinal health?
… until 12 months of age. Suggesting increased bacterial translocation, liver bacterial load was increased in AKR1D1 KO mice. Toll-like receptor 4 (TLR4) signalling was upregulated in the female mice, as was the pan-macrophage marker, F4/80, at mRNA and protein level. Suggestive of impaired …
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Role of Myosin Light Chain Kinase in Binge Ethanol and Burn Injury-Induced Intestinal Barrier Dysfunction
… after ethanol exposure and burn injury. Bacterial translocation along with immunofluorescent staining for tight junction protein localization will be performed to investigate intestinal barrier function and integrity. MLCK activation will be determined by Western blot analysis. Inhibition …
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The effect of butyrate-supplemented total parenteral nutrition on muc2 mRNA and goblet cell chemotypes in a short bowel syndrome neonatal piglet model
Background: Compromised barrier function and bacterial translocation are common complications of short bowel syndrome (SBS) and parenteral nutrition (PN). Although mucins help prevent intestinal bacteria translocation, total mucin production has been shown to decrease during PN infusion. Butyrate …
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Investigating the role of the gut microbiota on immune checkpoint inhibitor-mediated colitis
… examining these mice demonstrated increased bacterial translocation to mesenteric lymph nodes, indicating that intestinal microbial dysbiosis in this setting led to an impairment in intestinal barrier function. Gained knowledge through patient profiling and pre-clinical mouse models will …
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EXAMINATION OF THE EFFECTIVENESS OF PROVISION OF FUNCTIONAL AMINO ACIDS TO ENHANCE ROBUSTNESS IN ENTERIC CHALLENGED PIGS
… performance, suppressed ST shedding, and reduced bacterial translocation to spleen in pigs placed onto a common grower diet and subsequently challenged with ST. However, the positive effects were observed particularly in normal birth weight (NBW), but not LBW pigs, which had aggravated …
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Evaluation and Selection of a Bacillus based Direct-Fed Microbial Candidate for In situ Enzyme Production to Improve Gut Health Integrity, Bone Quality and Growth Performance in Poultry
… prophylactic practice to reduce the incidence of bacterial gastrointestinal diseases. Therefore, the objectives of the present dissertation were to evaluate and select different Bacillus spp. strains as DFM candidates based on enzyme production profiles to improve nutrient absorption and …
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The Role of Bacterial Amyloids In Regulating Gastrointestinal Homeostasis
Many bacterial species exist in nature as part of highly structured multicellular communities known as biofilms. Amyloids, proteins with a conserved β-sheet quarternary structure, show high resistance to many chemical and enzymatic processes including proteinase K and SDS treatments and are …
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Translocación Bacteriana en trauma abdominal e infección posoperatoria
Antecedentes: la Translocación Bacteriana (TB) describe el paso de bacterias residentes en el tracto gastrointestinal a tejidos normalmente estériles como los ganglios linfáticos mesentéricos (GLMs) y a otros órganos internos. Hasta el momento no ha sido demostrada la asociación de infección …
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Immunoprotective effects of lipopolysaccharide detoxification by a novel microbial-derived alkaline phosphatase
… increased incidence of diarrhea, increased bacterial translocation and endotoxin load, and increased mortality. Increased concentrations of LPS in circulation perpetuate post-wean syndrome and drive further gastrointestinal tract (GIT) morphological and digestive perturbations. Weaning is …