Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 270 for “"Bacterial infections"”.
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Experimental anaerobic bacterial infections in mice
… large subcutaneous abscesses at the site of bacterial injection in approximately 90% of the mice. The abscess can be seen as an obvious swelling within 5-7 days post-injection. The infection was initiated by injection of pure cultures grown in a semisolid medium. Similar infections were also …
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Treatment of bacterial infections by intradermal medication
A General Practitioner is not capable of scientific observation. He is easily prejudiced in favour of any new treatment, and has not the means at hand to test out results, using controls &c. But his greatest interest is in treatment. if any method: of treatment will relieve his patients of their …
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New Tools for Diagnosis and Treatment of Bacterial Infections
… common cause of hospital- and community-acquired bacterial infections. The approach relies on nanoparticle-mediated microfluidic capture and electrochemical detection of clinically relevant concentrations of bacteria directly from patient nasal swab specimens. Next, an integrated and automated …
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Targeting bacterial infections by using immunomodulatory host defence peptides and proteins
Bacterial infections and sepsis are amongst the leading causes of death worldwide. Sepsis is caused by an uncontrolled systemic host response towards an invading pathogen. Due to the engagement of various systems including cellmediated responses, the coagulation and complement cascades, treatment …
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Investigating Pulmonary Immune Responses that Detect and Counteract Gram-negative Bacterial Infections
Infections of the lungs can cause tremendous tissue damage which often leads to pathogens spreading into the bloodstream. In the airways, Gram-negative bacteria produce biofilms through exopolysaccharide (EPS) that provides microbial protection; however, the impact of EPS on detection remains …
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Investigations into novel signalling pathways in the response to viral and bacterial infections
… understanding the immune response to viral and bacterial perturbation of host signalling pathways. The TIR-domain containing adaptor TRAM is a relatively understudied protein with regard to TLR signalling, particularly with respect to type-I inferferon production. A re-evaluation of the role of …
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Novel Diagnostic Methods for Rapid Detection and Identification of Bacterial Infections in Bovine Mastitis
Bacterial infections affect the lives of millions of individuals worldwide. When a patient is diagnosed with an infection, the exact cause is often unknown. Microbial diagnostics rely on methods requiring the growth of a bacterial colony, including lengthy and time-consuming culturing techniques …
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Nutritional modeling of bacterial infections : physiology and metabolism of Pseudomonas aeruginosa during growth in cystic fibrosis sputum
The Gram-negative bacterium Pseudomonas aeruginosa is a notorious opportunistic pathogen of individuals with the genetic disease cystic fibrosis (CF). Pseudomonas aeruginosa establishes a chronic infection within the CF lung, where the sputum accumulation characteristic of CF provides a complex and …
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The value of certain theraputic agents against the bacterial infections causing conjunctivitis and rhinitis in dogs affected with distemper
Thesis (Ph. D.)--Michigan State University of Agriculture and Applied Science. Dept. of Bacteriology and Public Health, 1951
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Analysing M. abscessus-macrophage interactions and investigating treatments for M. abscessus and S. aureus intracellular bacterial infections, using a continuously growing, primary cell model of lung alveolar macrophages
… (MAB) and Staphylococcus aureus (SA) are bacterial pathogens capable of causing a range of infections in humans, and pulmonary infections are significant amongst them. During pulmonary infection, alveolar macrophages (AMs), as sentinel immune cells of the airways, are key cells for the …
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Synthesis and Characterization of Glycomaterials for Antibacterial Applications
… millions of people contract antibiotic-resistant bacterial infections, and tens of thousands die from infection-related complications in the United States alone. Bacterial infections are one of the leading causes of death worldwide, especially in healthcare institutes such as hospitals and nursing …
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Innovation in antimicrobial resistance: development of new antimicrobials and coadjutants to successfully treat bacterial infections [Innovazione nella resistenza antimicrobica: sviluppo di nuovi antimicrobici e coadiuvanti per trattare in modo efficace le infezioni batteriche]
L’aumento della resistenza dei patogeni batterici agli agenti antimicrobici costituisce una grave minaccia per la salute pubblica, determinando un incremento dei tassi di malattia e morte. I ceppi di batteri Gram-positivi e Gram-negativi resistenti ai farmaci stanno diventando sempre più difficili …
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The role of Cysteinyl leukotriene type 1 receptor (CysLTR1) during Listeria monocytogenes and mycobacterium tuberculosis infections in mice
… and allergic responses, its function during bacterial infections remains unclear. Our study aims to elucidate the role of CysLTR1 in disease progression using C57BL/6 and Balb/c mice infected either with Listeria monocytogenes (Lm) or with Mycobacterium tuberculosis (Mtb). Using CysLTR1 …
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The Potential Role of Cathelicidin Peptides for the Treatment of Lower Respiratory Tract Infections
Bacterial pneumonia, one of the leading causes of hospitalization and mortality worldwide, is caused by the colonization of invasive bacteria in the airways, leading to pulmonary inflammation and lung dysfunction. The development of antibiotic resistant bacterial infections has limited the …
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Electrochemical Detection of Anti-Biofilm Activity Using Unnatural Amino Acid-Containing Antimicrobial Peptides
Bacterial infections are a significant health problem that can be detrimental to the human population. It is estimated that bacterial infections are responsible for billions of dollars’ worth of damages in the health care field alone, and numerous deaths annually. Bacterial infections can become so …
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Bacteria-targeting nanoparticles for managing infections
Bacterial infections continue to be a significant concern particularly in healthcare settings and in the developing world. Current challenges include the increasing spread of drug resistant (DR) organisms, the side effects of antibiotic therapy, the negative consequences of clearing the commensal …
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Visualizing the attack of bacteria by the antimicrobial peptide human defensin 5
Bacterial infections are a major cause of concern in healthcare because of a rise in antibiotic-resistant bacteria and an increase in hospital-acquired infections. In order to combat bacterial infections, we need fundamental understanding of the host-pathogen interaction. As a part of the innate …
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Combating biofilms and antibiotic resistance using synthetic biology
Bacterial infections represent a significant source of morbidity and mortality. Biofilms and antibiotic resistance pose challenges to our future ability to treat bacterial diseases with antibiotics (1). Bacteria frequently live in biofilms, which are surface-associated communities encased in a …
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