Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Bacterial genetics"”.
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Gene Regulation of Tartrate Metabolism in Salmonella typhimurium
… unexplored area of Salmonella metabolism. Bacterial genetics and traditional biochemical methods such as -galactosidase transcriptional reporters and Electrophoretic Mobility Shift Assays (EMSA) allowed us to create a specific model for the gene regulation of L-tartrate metabolism. …
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Characterization and application of type VI-B RNA-targeting CRISPR systems
… VI-B. Using a combination of biochemistry and bacterial genetics, we demonstrated that the predicted nuclease of the VI-B system, Casl3b, is an RNA-guided RNase, whose activity can be modulated by the csx genes that often appear in genetic proximity to casl3b. Next, we characterized the …
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The Influence Of Host Genetics And Different <i>Mycobacterium tuberculosis</i> Strains On Macrophage Functions And Clinical Outcome Of Tuberculosis Disease
… outcomes. Many studies have shown host and bacterial genetics are important factors in TB susceptibility and progression. I hypothesized that an impairment of macrophage phagocytic function, under the influence of genetic factors, may help explain the pathogenesis of the transition from …
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Genetic Manipulation of Bacteroides for Transient Colonization of Germ-free Mice
… to tease apart these dynamics by generating bacterial tools that limited bacterial exposure of germ-free mice to a certain time-period was explored in this thesis. I target genes in synthesis pathways of two uniquely-bacterial amino acids, meso-diaminopimelic acid (mDAP) and D-Alanine (D-Ala) …
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Alicaligenes faecalis : identification and study of its antagonistic properties against Botrytis cinerea
… in Balbc mice injected with live and heat-killed bacterial cells gave strong reactions with the homologous immunogen and with ATCC 15554, the type strain of A. taeca/is, but not with Escherichia coli or Enterobacter aerogens in immunoprecipitation and dot immunobinding assays. Growth of Botrytis …
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Rate zonal density gradient ultracentrifugation analysis of repair of radiation damage to the folded chromosome of Escherichia coli
… probe of the constraints on DNA~packaging in the bacterial chromosome. The extremely gentle lysis and unfolding procedures which were developed yielded undamaged, replicating genomes, thus permitting direct measurement of the formation and repair of DNA double-strand breaks at …
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Chromosomal location for a genetic determinant of chlortetracycline resistance in a strain of Staphylococcus aureus
Thesis (M.S.)--Michigan State University. Dept. of Microbiology and Public Health, 1970
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The Genomic Sequence and Annotation of Bacteriophage HK239
Bacteriophages are viruses that infect bacteria and they are the most numerous biological entities on Earth. Temperate phage can adopt two different lifestyles. In the lytic lifestyle, a phage injects its genome into the host and a controlled developmental program ensues. The phage DNA is …
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Pyrimidine Genes in Pseudomonas Species
This thesis is a comparative study of gene arrangements in Pseudomonas species, and is organized into three major sections. The first section compares gene arrangements for different pathways in Pseudomonas aeruginosa PAO1 to determine if the gene arrangements are similar to previous studies. It …
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Functional Analysis of FtsA-Mediated Recruitment of FtsK in Escherichia coli
<p>Bacterial cytokinesis requires precise coordination between cytoplasmic and periplasmic components of the divisome to ensure that membrane constriction and chromosome segregation occur in synchrony. The actin-like protein FtsA plays a central role in this process by tethering FtsZ to the …
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Defining the Requirements for Early Gene Expression in Bacteriophage HK639
<p>Lambdoid phages suppress transcription termination to fully express their genes. Antitermination of early gene expression in most lambdoid phages is mediated by an interaction between the N protein and a number of host-encoded factors. Bacteriophage HK022 does not rely on a protein for …