Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Bacterial defense systems"”.
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The evolutionary ecology of methylation-dependent bacterial defense systems
… which has driven the evolution of diverse host defense systems. Although recent years have seen a rapid expansion in defense system discovery, there remain considerable gaps in our understanding of the evolutionary ecology of MGEs and host defenses. Given the role of MGEs in spreading drug …
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Anti-phage defense as a driver of molecular innovation
… has been a catalyzing force for the creation of bacterial defense systems and corresponding phage evasion strategies. To counter phage predation, bacteria have developed a vast diversity of enzyme chemistries and molecular sensing mechanisms whose study has produced new biotechnological tools and …
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Restriction-Modification and CRISPR-Cas Systems: Cooperation Between Innate and Adaptive Immunity in Prokaryotes
… and kill them. Restriction-modification (RM) systems represent one such strategy. Generally, these systems provide defense by coordinating the activities of two distinct enzymes: a restriction endonuclease and a methyltransferase. Both enzymes recognize the same short DNA sequences. The …
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Molecular Mechanisms of Sensing and Synergy by Anti-Bacteriophage Immune Systems in Staphylococcus
… strategies in the form of genetically encoded systems to defend themselves. Immunity can be conceptualized as occurring in three fundamental stages. First, the immune system must identify an invading pathogen— either directly via recognition of a pathogen-associated molecular pattern (PAMP), or …