Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 12 of 12 for “"Bacterial Adaptation"”.
-
A STUDY OF BACTERIAL ADAPTATION TO ULTRAVIOLET LIGHT IN ULTRAPURE WATER SYSTEMS
… and kill microorganisms. Morespecifically, bacterial growth conditions and the UPW stimulation time were investigated.The two major UV lights sources, UV254 and UV 185, were compared. The resultingdeath rates of bacteria living in UPW indicate that UV 185 is very effective in …
-
Characterization of cyclic di-GMP binding by the sole Borrelia burgdorferi and Borrelia hermsii PilZ domain-containing proteins
… has been demonstrated to be important in bacterial adaptation. Borrelia deletion mutant phenotypes have shown that c-di-GMP regulates motility, infectivity, and enzootic cycle progression. As the only known receptors encoded by Borrelia, PlzA and PlzC characterization is necessary in …
-
On the Gram-positive bacterial cell wall.
… and its makeup dynamically changes as a part of bacterial adaptation. Peptidoglycan is the biopolymer that composes nearly half of the cell wall, and by studying peptidoglycan valuable insights can be gained into the structure and function of the cell wall. This dissertation examines the chemical …
-
High-throughput experimental and computational studies of bacterial evolution
… in this thesis is concerned with the study of bacterial adaptation on short and long timescales. In the first section, consisting of three chapters, I describe a recently developed high-throughput technology for probing gene function, transposon-insertion sequencing, and its application to the …
-
Identification of the role of the sal locus in streptococcus pyogenes virulence during host-pathogen interactions
… regulatory system, which facilitates bacterial adaptation by responding to environmental signals during host pathogen-interactions. The first goal of this project was to determine a role in virulence for the SalKR regulatory system. The complete deletion of the salKR genes in the wild …
-
Functional Genomics and physiology of growth initiation in Salmonella
Abstract Lag phase is a period of bacterial adaptation that occurs prior to cell division. The aim of this project was to characterise the processes used by Salmonella enterica serovar Typhimurium to escape from lag phase, and determine whether these processes are dependent on the bacterial …
-
Ecological genomics of mutualism decline in nitrogen-fixing bacteria
… the forces that maintain cooperation in nature. Bacterial mutualists in particular might evolve more quickly than other organisms in response to environmental changes, thanks to short generation times and horizontal gene transfer, providing an ideal system in which to address questions of …
-
Mechanisms of microbial-host interaction during asymptomatic bacteriuria
… and relevant model for studying microbial adaptation. After establishing significant numbers, the bacteria either cause severe disease, or an asymptomatic carrier state resembling the normal flora at other mucosal sites. Patients with asymptomatic bacteriuria (ABU) are protected from …
-
Physiological roles and regulation of the cryptic prophage-encoded small protein DicB and small RNA DicF in Escherichia coli
Bacterial adaptation to stress conditions is vital for their survival in different environments. In the past decade, the important roles that small RNAs (sRNAs) and small proteins perform in regulating the stress response in bacteria has become evident. While the roles of numerous sRNAs and small …
-
Response of intestinal Escherichia coli to dietary factors in the mouse intestine
… variability, little is known about the bacterial response at the cellular level. The objective of this work was to identify mechanisms that enable gut bacteria to adapt to dietary factors. For this purpose, germ-free mice monoassociated with the commensal Escherichia coli K-12 strain …
-
Studying the riboregulatory role of Hfq in Klebsiella pneumoniae using CLASH (crosslinking, ligation and sequencing of hybrids)
… to adapt, repair and safeguard themselves. Bacterial adaptation involves reprogramming several molecular pathways that regulate transcription, post-transcriptional regulation (PTR), and translation. Although transcription is an essential regulatory mechanism for gene expression, the …
-
The Effect of Select Biological and Environmental Factors on the Horizontal Gene Transfer and Functionality of the TOL Plasmid: A Case Study for Genetic Bioaugmentation
… readily under harsh environments where genetic adaptation is required for the survival of microorganisms. HGT could be useful for bioremediation to shift microbial communities in favor of degrading xenobiotics, persistent organic compounds, and emerging contaminants. In fact, it has been noted …