Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Bacillus Calmette-Guerin"”.
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Microencapsulation of Bacillus calmette-guerin for use in cancer immunotherapy.
Microencapsulation of Bacillus calmette-guerin for use in cancer immunotherapy.
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Comparison of immune responses induced by Bacillus calmette-Guerin when given at birth or at 6 weeks of age in Ugandan Infants
… care facility receive the tuberculosis vaccine Bacillus Calmette-Guerin (BCG) on the first day of life. Infants delivered at home receive BCG at their first health care facility visit at 6 weeks of age. Our aim was to determine the effect of this delay in BCG administration on the induced immune …
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Inhibition of Urothelial Carcinoma By Type I Interferon Activation of The Innate and Adaptive Immune Response
<p>Bacillus Calmette-Guerin (BCG) is the first line therapy for bladder cancer patients with non-invasive disease. However, roughly 40% of patients exhibit no response, tumor recurrence or tumor progression following BCG treatment. Type I interferon (IFN-I) has potent anti-tumor effects against …
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Understanding the Role of Mitochondria in Driving Antiviral Inflammatory Responses
… We conducted a pilot study to evaluate if Bacillus Calmette-Guerin (BCG) can restore function in aged macrophages. BCG is a potent inducer of trained immunity and was used during the COVID-19 pandemic to protect against severe disease. Interestingly, we found that BCG treatment in vivo …
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Effect of Systemic Versus Localized Bacillus Calmette-Guérin Immunotherapy on Bladder Cancer Progression: Novel Role for Trained Immunity
… (NMIBC) involves intravesical immunotherapy with Bacillus Calmette Guérin (BCG). Unfortunately, most patients do not respond fully to this therapy, and our understanding of the immunotherapeutic effect of BCG is incomplete. The tumor immune microenvironment (TiME) is known to influence responses …
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The impact of malaria on the immunogenicity and efficacy of mycobacterium bovis BCG vaccination against mycobacterium tuberculosis in mice
Background Bacillus Calmette-Guerin (BCG) remains the only licensed vaccine for use against tuberculosis (TB), however, it is poorly efficacious against pulmonary TB in adults. The poor efficacy has been attributed in part to coinfections with many other unrelated pathogens that overlap …