Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"BVM"”.
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Evaluation and Clinical Implementation of a Dual-Energy CT Stopping-Power Ratio Mapping Technique for Proton-Therapy Treatment Planning
… Technique built on a Basis Vector Model (JSIR-BVM), which effectively reconstructs basis materials by using the spectral information from two different energies. In previous studies, we successfully showed the potential of using the basis-material maps reconstructed with JSIR-BVM to estimate …
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Identifying and Reducing Variability, Improving Scaffold Morphology, and Investigating Alternative Materials for the Blood Vessel Mimic Lab Electrospinning Process
… and improvement of “Blood Vessel Mimics” (BVMs), tissue engineered constructs used to evaluate cellular response to vascular medical devices. Currently, cells are grown onto fibrous, porous tubes made using an in-house electrospinning process from PLGA, a biocompatible co-polymer. The …
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Tissue Engineering a Blood Vessel Mimic While Monitoring Contamination Through Sterility Assurance Testing
… of <em>in vitro </em>blood vessel mimics (BVMs) in Cal Poly’s Tissue Engineering Lab has introduced the possibility of assessing the characteristics of cellular response to past, present, and future intravascular devices that aim at treating coronary artery disease.</p> <p>This thesis aimed …
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The Bayesian validation metric : a framework for probabilistic model calibration and validation
… and develop the "Bayesian Validation Metric" (BVM) as a general model validation and testing tool. We show that the BVM can represent all the standard validation metrics - square error, reliability, probability of agreement, frequentist, area, probability density comparison, statistical …
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Design and prototyping of a low-cost portable mechanical ventilator
… by compressing a conventional bag-valve mask (BVM) with a pivoting cam arm, eliminating the need for a human operator for the BVM. An initial prototype was built out of acrylic, measuring 11.25 x 6.7 x 8 inches (285 x 170 x 200 mm) and weighing 9 lbs (4.1 kg). It is driven by a stepper motor …
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Biomass energy : a real estate investment perspective
… market. Therefore the Biomass Valuation Model (BVM), developed in Excel®, allow the critical technical and financial components to communicate effectively, which would help to determine the viability of the biomass investment projects with greater certainty. The BVM would be able to generate …
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Characterization and Implementation of a Decellularized Porcine Vessel as a Biologic Scaffold for a Blood Vessel Mimic
… must be addressed to create a truly biomemtic BVM. The current model uses expanded poly(terafluorethylene) [ePTFE] or poly(lactic-go-glycolide) [PLGA] as the choice material for the scaffold. EPTFE has several advantages as it is a widely recognized biomaterial. However, ePTFE is very expensive …
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Development of an In-Vitro Tissue Engineered Blood Vessel Mimic Using Human Large Vessel Cell Sources
… Specifically, in-vitro blood vessel mimics (BVM) have been developed to create a bench-top blood vessel model using human cells that can be used to test and evaluate vascular disease treatments and intravascular devices. Previous BVM work has used fat derived human microvascular endothelial …
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Development and Characterization of Tissue Engineered Blood Vessel Mimics Under "Diabetic" Conditions
… (DHCAECs). The characterization of these BVMs was achieved using immunofluorescence, scanning electron microscopy (SEM), and qPCR gene expression analysis. From this study, it was determined that HUVECs and DHCAECs are robust enough to be cultured in a high glucose environment – analogous …
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Imaging Techniques for Proton Range Determination in Proton Therapy
… method with a linear basis vector model (JSIR-BVM) was integrated with a clinical Monte Carlo-based treatment planning system (TPS) for dose prediction comparison with the standard stoichiometric SECT method. Percentage deviation from the ground-truth volume receiving 80% of the prescription …
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Implementation of Physiologic Pressure Conditions in a Blood Vessel Mimic Bioreactor System
… intravascular devices. The blood vessel mimic (BVM) system has been previously used to assess the tissue response to deployed stents, but under non-physiologic conditions. Since then, efforts have been made to improve the vessel and bioreactor’s ability to emulate in vivo conditions. The ability …
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Evaluation of Human Umbilical Vein Endothelial Cells in Blood Vessel Mimics Through Changes in Gene Expression and Caspase Activity
<p>Blood vessel mimics (BVMs) are simple tissue engineered blood vessel constructs intended for preclinical testing of vascular devices. This thesis developed and implemented methods to characterize two of these components. The first aim of this thesis investigated the effect of cell culture …
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Evaluation of Endothelial Cell Responses to Elevated Glucose
… a tissue-engineered Blood Vessel Mimic (BVM) to represent diabetic macrovascular disease could expedite design of new vascular devices specifically tailored to diabetic patients. In contribution toward this model, this thesis assessed Human Umbilical Vein Endothelial Cell (HUVEC) …
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Development and Optimization of Imaging and Image Quantification Techniques for Tissue-Engineered Blood Vessel Mimics
<p>Blood vessels mimics (BVMs) are tissue-engineered blood vessels used to test vascular devices in an environment that mimics some simple anatomical factors of native blood vessels. It is important to accurately and consistently assess tissue-engineered blood vessels, although there is currently a …
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Non-invasive ventilation during paediatric retrieval: a systematised review
… to occur in 2-4% of NIV transports, with use of BVM in 8/334 (2%), desaturation episodes in 9/290 (3%), apnoea in 11/290(4%) and administration of CPR in 0/290 (0%) cases being described. There was insufficient reporting of change in vital signs or clinical condition during transport for …