Global ETD Search

Novel mutations associated with resistance to BTK inhibitors and alternative treatment strategies

Qi, JialeiUniversität Ulm

ulm-diss Repository record for Novel mutations associated with resistance to BTK inhibitors and alternative treatment strategies (opens in a new tab)

Exploring the role of IRF4 in the sensitivity of mantle cell lymphoma cells to Bruton's Tyrosine Kinase inhibitors

Portnojs, Artjoms2025

… Therapy using Bruton’s tyrosine kinase (BTK) inhibitors has improved clinical outcomes but primary and secondary resistance to BTK inhibitor (BTKi) therapy affects more than half of MCL patients. Resistance most often arises through gene mutations in cells protected from BTKi effects …

plymouth Repository record for Exploring the role of IRF4 in the sensitivity of mantle cell lymphoma cells to Bruton's Tyrosine Kinase inhibitors (opens in a new tab)

Untersuchungen zur Expressionsregulation sowie Funktion zweier Kopf-Hals-Tumor-relevanter Onkogene: Bruton-Tyrosinkinase und Adenosinrezeptor 2B

Lesakova, KristinaUniversität Ulm

ulm-diss Repository record for Untersuchungen zur Expressionsregulation sowie Funktion zweier Kopf-Hals-Tumor-relevanter Onkogene: Bruton-Tyrosinkinase und Adenosinrezeptor 2B (opens in a new tab)

Novel approaches to assess cellular interactions and their role in the pathology and treatment of lymphoproliferative disorders

Frend, Frances Hilary Rose2022

… observation that highly effective small molecule inhibitors that target key components of the BCR signalling machinery, such as Bruton’s tyrosine kinase (BTK), disrupt the migratory behaviour of CLL cells, and that this may, at least in part, underlie their clinical effect. Detailed …

plymouth Repository record for Novel approaches to assess cellular interactions and their role in the pathology and treatment of lymphoproliferative disorders (opens in a new tab)