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Showing 1 to 1 of 1 for “"BRCA1 BRCT Domain"”.
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Assessing the Clinical Relevance of BRCA1 BRCT Domain Variants of Uncertain Significance
… cancers are inherited, with pathogenic germline BRCA1 and BRCA2 variants causing the majority of hereditary cases. While genetic testing is used to identify pathogenic BRCA variant carriers who would subsequently benefit from personalized screening, prophylactic and treatment steps, its …