Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"BRCA-1"”.
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An Examination of Dimensions of Perceived Behavioral Control Regarding Genetic Counseling and Testing for BRCA 1 and BRCA 2 in African-American Women at Moderate to High-Risk for Breast Cancer
… in genetic counseling and testing for BRCA 1/2. The goals of this mixed methods study were twofold; first, to explore levels of perceived behavioral control and general motivations regarding genetic counseling and testing for BRCA 1/2 in African-American women at moderate to high-risk …
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The discovery of small molecule inhibitors of poly(ADP-ribose) mediated cell death
… as personalized treatments for patients with the BRCA-1/-2 mutation. However, there is a lack of small molecule inhibitors of other important enzymes and proteins in this pathway. Therefore, described herein is the discovery and evaluation of small-molecule inhibitors of poly(ADP-ribose) …
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PARP inhibition in combination with radiation therapy for the treatment of feline oral squamous cell carcinoma
Feline oral squamous cell carcinoma (FOSCC) is a devastating tumor frequently palliated with radiation therapy (RT). Disappointingly, RT typically exerts marginal and transient tumor regression and new strategies to enhance RT efficacy are needed. Poly (ADP-ribose) polymerase (PARP) is a key …