Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"BRAFV600E mutation"”.
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Relation between F-18 FDG Uptake of PET/CT and BRAFV600E Mutation in Papillary Thyroid Cancer
PURPOSE: BRAFV600E mutation and F-18 fluorodeoxyglucose (FDG) uptake are potential prognostic factors of papillary thyroid cancer (PTC). This study was performed to investigate the relationship between the BRAFV600E mutation and F-18 FDG uptake in PTC. MATERIALS AND METHODS: We retrospectively …
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Expression of X-linked Inhibitor of Apoptosis Protein in Neoplastic Thyroid Disorder
… the association of XIAP expression and the BRAFV600E mutation and analyzed the association of XIAP expression and tumor recurrence in BRAFV600E prevalent PTC population. Expression of XIAP was evaluated with immunohistochemical staining using monoclonal anti-XIAP in 164 specimens of …
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Low grade gliomas treated at the University of Cape Town Academic Hospital complex: 2001-2017
… free survival (PFS) was 42.8%. The presence of a BRAFV600E mutation was checked in 4 patients since 2013, all had JPA histology, and all were negative. Discussion: Our patient demographic differed from published data with respect to younger age at presentation and female predominance. Time to …
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Procaspase-3 activation as a strategy to overcome resistance to targeted anticancer therapies
… the MAPK pathway. One of the oncogenic driver mutations in the MAPK pathway is the V600E mutation on the BRAF protein. More than 50% of melanomas harbor this mutation that can be drugged with a BRAFV600E inhibitor vemurafenib. Chapter 3 reports the synergistic activity of PAC-1 + vemurafenib …