Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"BMPR1B"”.
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SGK196 controls stem cell fates by promoting the degradation of TGFβ family receptors
… interactions with the type I BMP receptor (BMPR1B), suggesting that these polar residues may play a key role in arbitrating SGK196 activity. The functional effects of Sgk196 in Xenopus laevis animal caps and embryos are in agreement with the results in hESCs. Defects in Sgk196 depleted …
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BMP Signaling through BMPR1A is Required for Establishment of Pancreatic Laterality
… flanks the pancreatic bud. Bmp4, Bmp7, BmpR1a, BmpR1b, and BmpRII are expressed in the pre-pancreatic mesenchyme. Interestingly, Bmp4 is expressed asymmetrically along the gut in the mesogastrium, preceeding gut turning. Transgenic knock down of BMP signaling via the secreted BMP antagonist …
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Genetic and molecular factors regulating growth and morphology in Senegalese sole (Solea senegalensis)
… and vtg3, also ubiquitous DETs, and the gen bmpr1b close to malt1, suggesting that inflammatory processes and BMP signaling pathways could contribute to modifying the axial skeleton and, consequently, the body ellipticity. Finally, this thesis examined the genetic architecture of growth, with …
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Molekular-zytogenetische Untersuchungen und Expressionsanalysen des Multiplen Myeloms
Durch die Kombination von SKY-, Array-CGH-, und Expressionsnanalysen wurden ausgewählte MM-Zelllinien auf Aberrationen hin untersucht und diese genauer analysiert. 32 Myelom-Patienten wurden mittels Array-CGH-Analyse untersucht und aufgrund ihrer Aberrationen und der klinischen Daten durch eine …
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Characterisation of the molecular mechanisms of dopaminergic axonal growth and their impairment in Parkinson's disease
… α-synuclein. α-synuclein impaired both BMPR1B- and Smad1- mediated transcription, however, GDF5 and BMP2 treatment restored α-synuclein-mediated impairments in the BMP-Smad transcriptional response. Histone deacetylase (HDAC)5 also regulates the BMP-Smad pathway, and here we demonstrate …
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Bone morphogenetic protein (BMP-7) και μοριακά δίκτυα δυνητικών stem κυττάρων στον νεφρό
… την σηματοδότηση της BMP-7, μόριο του υποδοχέα BMPR1B, εκφράζεται στην κυτταροπλασματική μεμβράνη, στο κυτταρόπλασμα αλλά και στον πυρήνα των κυττάρων των ουροφόρων σωληναρίων. Η σαφής παρουσία του υποδοχέα BMPRIB στα κύτταρα των εγγύς σωληναρίων, μπορεί να υποστηρίζει την ενδεχόμενη δράση της …