Global ETD Search
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Showing 1 to 3 of 3 for “"BMP8B"”.
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Characterisation of BMP Processing and Signalling in Adipocytes
… However, the molecular mechanisms underlying BMP8B function in BAT remain unclear. It is reported that BMP8B signals through both SMAD1/5/8 and SMAD2/3 pathways in several cell types, but the impact of such unusual signalling specificity in adipocyte function is unknown. Thus, investigating …
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A Human Pluripotent Stem Cell-Derived Model for the Investigation of Thermogenic Adipocyte Development and Function
… of BAs. The bone morphogenetic protein 8B (BMP8B) has been identified in the mouse as a potential regulator of BA activity; however, its role in human BA function is unknown. Through the generation of a loss of function model of BMP8B I found that while a direct effect on BA differentiation …
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The regulation of the hepcidin by modulators of the bone morphogenetic protein (BMP) pathway
… BMP/SMAD pathway. Finally, the little known BMP, BMP8b, and the clotting factor, von Willebrand Factor which were also found to be significantly increased in the liver of the HPX mouse, were investigated as potential regulators of hepcidin. BMPSb has the potential to form heterodimeric complexes …